Department of Otolaryngology, Medical Academy, Lithuanian University of Health Sciences, Eivenių 2, Kaunas 50009, Lithuania.
Sleep Breath. 2013 May;17(2):695-703. doi: 10.1007/s11325-012-0744-9. Epub 2012 Jun 29.
The aim of this study was to assess the efficacy of radiofrequency treatment (RFT) of the soft palate and combined radiofrequency-assisted uvulopalatoplasty (RF-UPP) in the treatment of snoring and mild to moderate obstructive sleep apnea/hypopnea syndrome (OSAHS).
In the study group consisting of 32 snoring and mild to moderate OSAHS patients with excessive soft tissue of the soft palate or uvula, 13 patients underwent RFT of the soft palate and 19 patients underwent combined RF-UPP. The baseline and posttreatment polysomnography and clinical test battery consisting of Visual Analogue Scales (VAS), Lithuanian version of Sleep Apnea Quality of Life Index (SAQLI-LT), Spielberg's Trait-State Anxiety Inventory, Beck Depression Inventory-second edition (BDI-II), and Epworth Sleepiness Scale were applied to assess the treatment outcomes.
After a short-term follow-up of 2 to 3 months, the group of the RFT patients showed improvement in mean VAS snoring and SAQLI-LT scores, while the group of RF-UPP patients showed statistically significantly improvement in mean apnea-hypopnea index (AHI) (12.51 ± 7.66 vs. 7.88 ± 6.05, p < 0.05, β = 0.107), SAQLI-LT, and BDI-II scores. The group of RF-UPP patients had superior and statistically significant improvement compared to the RFT alone patients with regard to mean AHI (effect size 4.63 ± 4.65 vs. 0.95 ± 4.83, p < 0.05) and SAQLI-LT (effect size 0.75 ± 0.59 vs. 0.33 ± 0.40, p < 0.05) scores.
Combined RF-UPP showed to be effective in the treatment of snoring and mild to moderate OSAS overcoming the RFT alone.
本研究旨在评估射频治疗(RFT)软腭和联合射频辅助悬雍垂腭咽成形术(RF-UPP)治疗打鼾和轻中度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的疗效。
在由 32 例打鼾和轻中度 OSAHS 患者组成的研究组中,13 例患者接受了软腭 RFT,19 例患者接受了联合 RF-UPP。基线和治疗后的多导睡眠图和临床测试组合,包括视觉模拟量表(VAS)、立陶宛版睡眠呼吸暂停质量指数(SAQLI-LT)、斯皮尔伯格特质-状态焦虑量表、贝克抑郁量表第二版(BDI-II)和嗜睡量表,用于评估治疗效果。
在 2 至 3 个月的短期随访后,RFT 组患者的平均 VAS 打鼾和 SAQLI-LT 评分有所改善,而 RF-UPP 组患者的平均呼吸暂停低通气指数(AHI)(12.51±7.66 与 7.88±6.05,p<0.05,β=0.107)、SAQLI-LT 和 BDI-II 评分均有统计学显著改善。RF-UPP 组患者在平均 AHI(效应大小 4.63±4.65 与 0.95±4.83,p<0.05)和 SAQLI-LT(效应大小 0.75±0.59 与 0.33±0.40,p<0.05)评分方面的改善优于单独 RFT 组。
联合 RF-UPP 治疗打鼾和轻中度 OSAHS 比单独 RFT 更有效。