诱导分娩时的“胎膜早破”是足月初产妇行剖宫产术的一个危险因素。
"Early rupture of membranes" during induced labor as a risk factor for cesarean delivery in term nulliparas.
机构信息
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.
出版信息
PLoS One. 2012;7(6):e39883. doi: 10.1371/journal.pone.0039883. Epub 2012 Jun 29.
Abstract
OBJECTIVE
To determine if "early rupture of membranes" (early ROM) during induction of labor is associated with an increased risk of cesarean section in term nulliparas.
STUDY DESIGN
The rate of cesarean section and the timing of ROM during the course of labor were examined in term singleton nulliparas whose labor was induced. Cases were divided into 2 groups according the timing of ROM: 1)"early ROM", defined as ROM at a cervical dilatation<4 cm during labor; and 2) "late ROM", ROM at a cervical dilatation≥4 cm during labor. Nonparametric techniques were used for statistical analysis.
RESULTS
- In a total of 500 cases of study population, "early ROM" occurred in 43% and the overall cesarean section rate was 15.8%; 2) patients with "early ROM" had a higher rate of cesarean section and cesarean section due to failure to progress than did those with "late ROM" (overall cesarean section rate: 24%[51/215] vs. 10%[28/285], p<0.01; cesarean section rate due to failure to progress: 18%[38/215] vs. 8%[22/285], p<0.01 for each) and this difference remained significant after adjusting for confounding variables.
CONCLUSION
"Early ROM" during the course of induced labor is a risk factor for cesarean section in term singleton nulliparas.
摘要
目的
确定在引产过程中“胎膜早破”（早期 ROM）是否与足月初产妇剖宫产率增加有关。
研究设计
检查了引产足月单胎初产妇的剖宫产率和产程中 ROM 的时间。根据 ROM 的时间将病例分为 2 组：1）“早期 ROM”，定义为产程中宫颈扩张<4 cm 时 ROM；2）“晚期 ROM”，定义为产程中宫颈扩张≥4 cm 时 ROM。采用非参数技术进行统计分析。
结果
1）在总共 500 例研究人群中，“早期 ROM”占 43%，总体剖宫产率为 15.8%；2）与“晚期 ROM”相比，“早期 ROM”患者剖宫产率和因进展失败而进行的剖宫产率更高（总剖宫产率：24%[51/215] vs. 10%[28/285]，p<0.01；因进展失败而进行的剖宫产率：18%[38/215] vs. 8%[22/285]，p<0.01 各有），并且在调整混杂变量后这种差异仍然显著。
结论
在引产过程中“早期 ROM”是足月单胎初产妇剖宫产的一个危险因素。
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3
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ACOG Practice Bulletin No. 107: Induction of labor.
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The labor induction: integrated clinical and sonographic variables that predict the outcome.
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