Section of Adolescent Medicine, Indiana University School of Medicine, Indianapolis, USA.
Patient Educ Couns. 2012 Oct;89(1):184-90. doi: 10.1016/j.pec.2012.06.010. Epub 2012 Jul 5.
To evaluate Positive Choices (PC), a program that employed lay health workers to motivate antiretroviral adherence among persons living with HIV with coverage from Indiana's high-risk insurance pool.
Four hundred and forty nine participants living in the greater Indianapolis area were randomly allocated to treatment (n = 91) or control (n = 358) groups and followed for one year.
Compared to control subjects, PC subjects were more likely to adhere to HIV medications (medication possession ratio adherence ≥ 0.95, OR = 1.83, p = 0.046), and to achieve undetectable viral load (<50 copies/mL, OR = 2.01, p = 0.011) in the 12 months following introduction of PC. There were no significant differences observed between groups in any of self-reported health status indicators.
Estimates suggest that PC clients were 16% more likely to have undetectable viral loads than clients in standard care. The incremental program cost was approximately $10,000 for each additional person who achieved an undetectable viral load.
As persons living with HIV experience greater longevity and healthcare reform expands coverage to these high-risk populations, greater demands will be placed on the HIV-care workforce. Results suggest lay health workers may serve as effective adjuncts to professional care providers.
评估“积极选择”(PC)项目,该项目雇佣非专业卫生工作者来激励艾滋病毒感染者的抗逆转录病毒药物依从性,该项目的覆盖范围来自印第安纳州高风险保险池。
449 名居住在印第安纳波利斯大都市区的参与者被随机分配到治疗组(n = 91)或对照组(n = 358),并随访一年。
与对照组相比,PC 组更有可能坚持服用 HIV 药物(药物持有率依从性≥0.95,OR = 1.83,p = 0.046),并且在引入 PC 后 12 个月内实现病毒载量不可检测(<50 拷贝/mL,OR = 2.01,p = 0.011)。在任何自我报告的健康状况指标方面,两组之间均无显著差异。
估计表明,PC 客户的病毒载量不可检测率比标准护理客户高 16%。对于每增加一个病毒载量不可检测的人,该增量项目的成本约为 1 万美元。
随着艾滋病毒感染者的寿命延长,医疗改革扩大了对这些高危人群的覆盖范围,对艾滋病毒护理劳动力的需求将会增加。结果表明,非专业卫生工作者可能是专业护理提供者的有效辅助。