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果胶凝胶在生物医学应用方面的进展。

Advances in biomedical applications of pectin gels.

机构信息

Laboratorio di Biomateriali, Bioengineering Department and UdR INSTM Milano Politecnico, Politecnico di Milano, P.zza Leonardo da Vinci 32, 20133 Milan, Italy.

出版信息

Int J Biol Macromol. 2012 Nov;51(4):681-9. doi: 10.1016/j.ijbiomac.2012.07.002. Epub 2012 Jul 7.

Abstract

Pectin, due to its simple and cytocompatible gelling mechanism, has been recently exploited for different biomedical applications including drug delivery, gene delivery, wound healing and tissue engineering. Recent studies involving pectin for the biomedical field are reviewed, with the aim to capture the state of art on current research about pectin gels for biomedical applications, moving outside the traditional fields of application such as the food industry or pharmaceutics. Pectin structure, sources and extraction procedures have been discussed focussing on the properties of the polysaccharide that can be tuned to optimize the gels for a desired application and possess a fundamental role in application of pectin in the biomedical field.

摘要

由于其简单且细胞相容的胶凝机制,果胶最近被用于不同的生物医学应用,包括药物输送、基因输送、伤口愈合和组织工程。综述了涉及生物医学领域的果胶的最新研究,旨在捕捉当前关于生物医学应用中果胶凝胶的研究现状,超越传统的应用领域,如食品工业或制药业。讨论了果胶的结构、来源和提取过程,重点介绍了多糖的性质,这些性质可以被调整以优化凝胶的性能,使其适用于特定的应用,并且在果胶在生物医学领域的应用中起着重要作用。

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