Serra S, Monteiro P, Vaz A, Pires E, Monteiro R, Inês L, Salvador M J, Bernardo J, Malcata A
Serviço de Reumatologia, Hospitais da Universidade de Coimbra, Portugal.
Acta Reumatol Port. 2012 Jan-Mar;37(1):70-4.
The authors describe a 54 year-old male patient, admitted after presenting in the emergency room with acute oligoarthritis affecting the shoulders and right tibiotarsal and sternoclavicular joints, with a week's duration. He was non-febrile and related a purulent discharge from the stump of a traumatic amputation of the left thumb, starting a few days prior to the presenting complaints. There was a previous history of gouty arthritis and moderate alcoholism. Lab work revealed an elevation of the acute phase markers, with marked neutrophilia. Upon admittance, the patient underwent arthrocentesis, revealing a purulent discharge with sodium monourate crystals, which cultured positively for meticillin-sensitive Staphylococcus aureus. Besides antibiotherapy, on Day 5 the patient presented with a cervical abscess with extension to mediastinum; the abscess was drained by a cardiothoracic surgeon, and the right sternoclavicular and first costochondral articulations were found to be destroyed. The authors note that, although it is a rare occurrence septic arthritis can coexist with gout, while discussing the possible mecanisms of this association, as well as particular details of the clinical case presented.
作者描述了一名54岁男性患者,因急性少关节炎累及双肩、右胫跗关节和胸锁关节,病程一周,在急诊室就诊后入院。他无发热,自述左拇指外伤性截肢残端有脓性分泌物,在出现当前症状前几天开始出现。既往有痛风性关节炎病史和中度酗酒史。实验室检查显示急性期标志物升高,伴有明显的中性粒细胞增多。入院时,患者接受了关节穿刺,抽出脓性分泌物,其中含有尿酸钠晶体,培养结果为对甲氧西林敏感的金黄色葡萄球菌阳性。除了抗生素治疗外,在第5天患者出现颈部脓肿并蔓延至纵隔;心胸外科医生对脓肿进行了引流,发现右胸锁关节和第一肋软骨关节已被破坏。作者指出,虽然脓毒性关节炎与痛风并存的情况罕见,但在讨论这种关联的可能机制以及所呈现临床病例的具体细节时提到了这一点。