采用亚30飞秒镱光纤激光振荡器的多模态显微镜。
Multimodal microscopy with sub-30 fs Yb fiber laser oscillator.
作者信息
Nie Bai, Saytashev Ilyas, Chong Andy, Liu Hui, Arkhipov Sergey N, Wise Frank W, Dantus Marcos
出版信息
Biomed Opt Express. 2012 Jul 1;3(7):1750-6. doi: 10.1364/BOE.3.001750. Epub 2012 Jun 27.
Abstract
Nonlinear optical microscopy with sub-30 fs pulses from an Yb-fiber laser, approximately three times shorter than typical fiber laser pulses, leads to an order of magnitude brighter third harmonic generation imaging. Multiphoton fluorescence, second and third harmonic generation modalities are compared on stained microspheres and unstained biological tissues.
摘要
使用来自镱光纤激光器的亚30飞秒脉冲的非线性光学显微镜，其脉冲大约比典型光纤激光脉冲短三倍，可使三次谐波产生成像亮度提高一个数量级。在染色微球和未染色生物组织上比较了多光子荧光、二次和三次谐波产生模式。
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