基于目标杂交诱导 DNA 探针柔韧性变化的双信号电化学 DNA 传感器。
A dual-signalling electrochemical DNA sensor based on target hybridization-induced change in DNA probe flexibility.
机构信息
University of Nebraska-Lincoln, 651 Hamilton Hall, Lincoln, NE 68588-0304, USA.
出版信息
Chem Commun (Camb). 2012 Sep 7;48(69):8703-5. doi: 10.1039/c2cc34312f. Epub 2012 Jul 24.
PMID:22825042
Abstract
We report a fully covalent, dual-signalling electrochemical DNA sensor that exploits competitive binding and target hybridization-induced change in probe flexibility for simple and robust detection of target DNA.
摘要
我们报道了一种完全共价的、双信号电化学 DNA 传感器，该传感器利用竞争结合和目标杂交诱导探针灵活性的变化，实现了对目标 DNA 的简单、稳健的检测。
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