通气阈与间歇性跛行患者的行走耐力相关。
Ventilatory threshold is related to walking tolerance in patients with intermittent claudication.
作者信息
da Rocha Chehuen M, Cucato G, Dos Anjos Souza Barbosa J, Costa L, Ritti-Dias R, Wolosker N, de Moraes Forjaz C
机构信息
Exercise Hemodynamic Laboratory, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil.
出版信息
Vasa. 2012 Jul;41(4):275-81. doi: 10.1024/0301-1526/a000203.
BACKGROUND
This study assessed the relationship between lower limb hemodynamics and metabolic parameters with walking tolerance in patients with intermittent claudication (IC).
PATIENTS AND METHODS
Resting ankle-brachial index (ABI), baseline blood flow (BF), BF response to reactive hyperemia (BFRH), oxygen uptake (VO2), initial claudication distance (ICD) and total walking distance (TWD) were measured in 28 IC patients. Pearson and Spearman correlations were calculated.
RESULTS
ABI, baseline BF and BF response to RH did not correlate with ICD or TWD. VO2 at first ventilatory threshold and VO2peak were significantly and positively correlated with ICD (r = 0.41 and 0.54, respectively) and TWD (r = 0.65 and 0.71, respectively).
CONCLUSIONS
VO2peak and VO2 at first ventilatory threshold, but not ABI, baseline BF and BFHR were associated with walking tolerance in IC patients. These results suggest that VO2 at first ventilatory threshold may be useful to evaluate walking tolerance and improvements in IC patients.
背景
本研究评估间歇性跛行（IC）患者下肢血流动力学和代谢参数与步行耐力之间的关系。
患者与方法
对28例IC患者测量静息踝肱指数（ABI）、基线血流（BF）、充血反应性充血时的BF反应（BFRH）、摄氧量（VO2）、初始跛行距离（ICD）和总步行距离（TWD）。计算Pearson和Spearman相关性。
结果
ABI、基线BF和对RH的BF反应与ICD或TWD均无相关性。第一通气阈值时的VO2和VO2峰值与ICD（分别为r = 0.41和0.54）和TWD（分别为r = 0.65和0.71）显著正相关。
结论
VO2峰值和第一通气阈值时的VO2与IC患者的步行耐力相关，而ABI、基线BF和BFHR则不然。这些结果表明，第一通气阈值时的VO2可能有助于评估IC患者的步行耐力及改善情况。
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