Department of Bioengineering and the Neurosciences Program, Stanford University, Stanford, California, USA.
Nat Neurosci. 2012 Jul 26;15(8):1058-60. doi: 10.1038/nn.3172.
Natural or artificially induced electrical activity changes can alter ion balance so as to briefly influence firing. An optogenetics study delineates one mechanism: Cl- shifts causing seconds-long excitability changes after silencing.
自然或人为诱导的电活动变化可以改变离子平衡,从而短暂影响放电。一项光遗传学研究描绘了一种机制:氯离子转移导致沉默后数秒钟的兴奋性变化。