杂多酸催化炔丙醇和烯丙醇的直接脱氧反应。
Heteropolyacid-catalyzed direct deoxygenation of propargyl and allyl alcohols.
机构信息
School of Pharmaceutical Sciences, University of Shizuoka, 52-1, Yada, Suruga-ku, Shizuoka, Shizuoka 422-8526, Japan.
出版信息
J Org Chem. 2012 Aug 17;77(16):7092-7. doi: 10.1021/jo300889p. Epub 2012 Aug 9.
The combination of H(3)[PW(12)O(40)]·nH(2)O (1 mol %) and Et(3)SiH led to the direct catalytic deoxygenation of propargyl alcohols, in which proper solvent selection Cl(CH(2))(2)Cl vs CF(3)CH(2)OH was the key to obtaining better product yields. Under similar conditions, the deoxygenation of allyl alcohols proceeded to give thermodynamically stable alkenes with migration of the double bonds in good yields.
H(3)[PW(12)O(40)]·nH(2)O（1 mol %）与 Et(3)SiH 的组合导致炔丙醇的直接催化脱氧，其中适当的溶剂选择 Cl(CH(2))(2)Cl 与 CF(3)CH(2)OH 是获得更好产物收率的关键。在类似条件下，烯丙醇的脱氧反应以热力学稳定的烯烃形式进行，并且双键迁移，收率良好。
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