Singh Saroj, Singh Ankita, Srivastava Uma
S.N. Medical College, Agra, India.
J Obstet Gynaecol India. 2011 Aug;61(4):404-7. doi: 10.1007/s13224-011-0059-y. Epub 2011 Sep 22.
To compare the efficacy and safety of patient controlled epidural analgesia with basal continuous infusion versus intermittent bolus for labor analgesia using fentanyl and bupivacaine.
In this prospective study, 60 parturients having singleton term uncomplicated pregnancy in early active labor were included. 30 parturients were allocated to receive patient controlled epidural analgesia + basal continuous infusion (Group-A) and 30 received intermittent bolus on demand (Group-B). Efficacy of technique was assessed in terms of quality of analgesia on 0-10 cm verbal analogue scale. Effect on labor was assessed by duration of labor, mode of delivery, and parturient's satisfaction. Neonatal outcome was measured by Apgar score. Data were expressed as mean ± SD and analysed using Student 't' test and chi square test where appropriate. P < 0.05 was considered statistically significant.
Analgesic efficacy of both the groups was comparable. Maternal satisfaction was better in group A than in group B but the results did not achieve statistical significance. Effect on labor and neonatal outcome were comparable.
Both the techniques appear to be safe for the mother and neonate with excellent analgesic efficacy. In a busy obstetric unit with increased demand of epidural analgesia, patient controlled epidural analgesia with basal continuous infusion may be preferred.
比较使用芬太尼和布比卡因的患者自控硬膜外镇痛联合基础持续输注与间断推注用于分娩镇痛的疗效和安全性。
在这项前瞻性研究中,纳入了60例单胎足月妊娠且处于早期活跃期的无并发症产妇。30例产妇被分配接受患者自控硬膜外镇痛+基础持续输注(A组),30例按需接受间断推注(B组)。根据0至10厘米视觉模拟量表上的镇痛质量评估该技术的疗效。通过产程、分娩方式和产妇满意度评估对分娩的影响。通过阿氏评分衡量新生儿结局。数据以均值±标准差表示,并在适当情况下使用学生t检验和卡方检验进行分析。P<0.05被认为具有统计学意义。
两组的镇痛效果相当。A组产妇的满意度高于B组,但结果未达到统计学意义。对分娩和新生儿结局的影响相当。
两种技术对母亲和新生儿似乎都是安全的,镇痛效果极佳。在硬膜外镇痛需求增加的繁忙产科病房,患者自控硬膜外镇痛联合基础持续输注可能更受青睐。