Should an IRB approve a placebo-controlled randomized trial of analgesia for procedural pain in neonates?
作者信息
Bellieni Carlo V, Taddio Anna, Linebarger Jenni S, Lantos John D
机构信息
Department of Neonatology, Siena University Hospital, Siena, Italy.
出版信息
Pediatrics. 2012 Sep;130(3):550-3. doi: 10.1542/peds.2011-2910. Epub 2012 Aug 13.
Abstract
摘要
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Should an IRB approve a placebo-controlled randomized trial of analgesia for procedural pain in neonates?机构审查委员会是否应批准一项针对新生儿程序性疼痛的镇痛安慰剂对照随机试验？
Pediatrics. 2012 Sep;130(3):550-3. doi: 10.1542/peds.2011-2910. Epub 2012 Aug 13.
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Placebo use in the N-of-1 trial.在单病例试验中使用安慰剂。
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The analgesic properties of intraoral sucrose: an integrative review.口腔内蔗糖的镇痛特性：一项综合综述。
Adv Neonatal Care. 2011 Apr;11(2):83-92; quiz 93-4. doi: 10.1097/ANC.0b013e318210d043.
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Epidemiology and management of painful procedures in children in Canadian hospitals.加拿大医院中儿童有痛操作的流行病学和管理。
CMAJ. 2011 Apr 19;183(7):E403-10. doi: 10.1503/cmaj.101341. Epub 2011 Apr 4.
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Heel blood sampling in European neonatal intensive care units: compliance with pain management guidelines.足跟采血在欧洲新生儿重症监护病房中的应用：疼痛管理指南的执行情况。
Arch Dis Child Fetal Neonatal Ed. 2011 Jan;96(1):F65-8. doi: 10.1136/adc.2010.186429.
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Analgesic effects of sweet-tasting solutions for infants: current state of equipoise.甜味溶液对婴儿的镇痛效果：目前处于均衡状态。
Pediatrics. 2010 Nov;126(5):894-902. doi: 10.1542/peds.2010-1593. Epub 2010 Oct 11.
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No analgesia to the control group: is it acceptable?对照组不进行镇痛：这可以接受吗？
Pediatrics. 2010 Mar;125(3):e709; author reply e709-10. doi: 10.1542/peds.LTE.0310a.
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Sucrose for analgesia in newborn infants undergoing painful procedures.蔗糖用于接受疼痛性操作的新生儿镇痛。
Cochrane Database Syst Rev. 2004(3):CD001069. doi: 10.1002/14651858.CD001069.pub2.
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Do we still hurt newborn babies? A prospective study of procedural pain and analgesia in neonates.我们仍在伤害新生儿吗？一项关于新生儿程序性疼痛与镇痛的前瞻性研究。
Arch Pediatr Adolesc Med. 2003 Nov;157(11):1058-64. doi: 10.1001/archpedi.157.11.1058.
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Consensus statement for the prevention and management of pain in the newborn.新生儿疼痛预防与管理的共识声明。
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