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透明质酸在伤口愈合中的作用。

The role of hyaluronan in wound healing.

作者信息

Frenkel Joseph S

机构信息

Wound Healing Research Unit, Department of Wound Healing, School of Medicine, Cardiff University, Melbourne, Victoria, Australia.

出版信息

Int Wound J. 2014 Apr;11(2):159-63. doi: 10.1111/j.1742-481X.2012.01057.x. Epub 2012 Aug 14.

Abstract

The polysaccharide hyaluronan (HA) (synonyms - hyaluronic acid, hyaluronate) is a versatile, polymorphic, glycosoaminoglycan with vast biological functions. HA is found throughout the body, primarily residing in skin, thus playing an important role in wound healing. Research regarding HA's function has changed over the years, primarily focussing on a particular aspect or function. The contribution of HA in each stage of normal wound healing as well as its clinical wound dressing applications will be examined.

摘要

多糖透明质酸(HA)(同义词——透明质酸、透明质酸盐)是一种具有多种生物学功能的多功能、多形态糖胺聚糖。HA遍布全身,主要存在于皮肤中,因此在伤口愈合中发挥着重要作用。多年来,关于HA功能的研究不断变化,主要集中在某个特定方面或功能上。本文将探讨HA在正常伤口愈合各阶段的作用及其在临床伤口敷料中的应用。

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本文引用的文献

1
Efficacy and safety of hyaluronic acid in treatment of leg ulcers: a double-blind RCT.
J Wound Care. 2012 Mar;21(3):131-2, 134-6, 138-9. doi: 10.12968/jowc.2012.21.3.131.
2
Wound healing through synergy of hyaluronan and an iodine complex.
J Wound Care. 2011 Sep;20(9):424, 426, 428-30. doi: 10.12968/jowc.2011.20.9.424.
3
Evaluation of the physical and biological properties of hyaluronan and hyaluronan fragments.
Int J Pharm. 2011 Nov 25;420(1):84-92. doi: 10.1016/j.ijpharm.2011.08.031. Epub 2011 Aug 22.
5
Hyaluronan as an immune regulator in human diseases.
Physiol Rev. 2011 Jan;91(1):221-64. doi: 10.1152/physrev.00052.2009.
6
Role of hyaluronan in angiogenesis and its utility to angiogenic tissue engineering.
Organogenesis. 2008 Oct;4(4):203-14. doi: 10.4161/org.4.4.6926.
7
Hyaluronan in skin: aspects of aging and its pharmacologic modulation.
Clin Dermatol. 2008 Mar-Apr;26(2):106-22. doi: 10.1016/j.clindermatol.2007.09.013.
8
Differential effects of hyaluronan and its fragments on fibroblasts: relation to wound healing.
Wound Repair Regen. 2008 Mar-Apr;16(2):274-87. doi: 10.1111/j.1524-475X.2007.00342.x. Epub 2008 Feb 13.
9
A case report of the treatment of diabetic foot ulcers using a sodium hyaluronate and iodine complex.
Int J Low Extrem Wounds. 2007 Sep;6(3):143-7. doi: 10.1177/1534734607304684.
10
Hyaluronan in tissue injury and repair.
Annu Rev Cell Dev Biol. 2007;23:435-61. doi: 10.1146/annurev.cellbio.23.090506.123337.

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