Frenkel Joseph S
Wound Healing Research Unit, Department of Wound Healing, School of Medicine, Cardiff University, Melbourne, Victoria, Australia.
Int Wound J. 2014 Apr;11(2):159-63. doi: 10.1111/j.1742-481X.2012.01057.x. Epub 2012 Aug 14.
The polysaccharide hyaluronan (HA) (synonyms - hyaluronic acid, hyaluronate) is a versatile, polymorphic, glycosoaminoglycan with vast biological functions. HA is found throughout the body, primarily residing in skin, thus playing an important role in wound healing. Research regarding HA's function has changed over the years, primarily focussing on a particular aspect or function. The contribution of HA in each stage of normal wound healing as well as its clinical wound dressing applications will be examined.
多糖透明质酸(HA)(同义词——透明质酸、透明质酸盐)是一种具有多种生物学功能的多功能、多形态糖胺聚糖。HA遍布全身,主要存在于皮肤中,因此在伤口愈合中发挥着重要作用。多年来,关于HA功能的研究不断变化,主要集中在某个特定方面或功能上。本文将探讨HA在正常伤口愈合各阶段的作用及其在临床伤口敷料中的应用。