Serbetçi Tuba, Birteksöz Seher, Prado Soizic, Michel Sylvie, Tillequin François
Department of Pharmacognosy, Faculty of Pharmacy, Istanbul University, 34116 Istanbul, Turkey.
Nat Prod Commun. 2012 Jul;7(7):891-4.
A series of 3,3-dimethyl-3Hbenzothieno[3,2-f][1]-benzopyran analogues modified at the pyran 1,2-double bond were synthesized. The corresponding dihydro and (+/-)-cis-diol derivatives were converted into diacetate and cyclic carbonate upon acylation. The title compounds were characterized by spectroscopic analysis and screened for their antimicrobial activity in vitro.
合成了一系列在吡喃1,2-双键处修饰的3,3-二甲基-3H-苯并噻吩并[3,2-f][1]-苯并吡喃类似物。相应的二氢和(+/-)-顺式二醇衍生物在酰化后转化为二乙酸酯和环状碳酸酯。通过光谱分析对标题化合物进行了表征,并对其体外抗菌活性进行了筛选。