Department of Zoology, Allan Wilson Centre for Molecular Ecology and Evolution, University of Otago, Dunedin, New Zealand.
Mol Ecol Resour. 2012 Nov;12(6):1161-7. doi: 10.1111/j.1755-0998.2012.03176.x. Epub 2012 Aug 27.
Preserving genetic health is an important aspect of species conservation. Allelic diversity is particularly important to conserve, as it provides capacity for adaptation and thus enables long-term population viability. Allele retention is difficult to predict beyond one generation for real populations with complex demography and life-history traits, so we developed a computer model to simulate allele retention in small populations. AlleleRetain is an individual-based model implemented in r and can be applied to assess management options for conserving allelic diversity in small populations of animals with overlapping generations. AlleleRetain remedies the limitations of similar existing software, and its source code is freely available for further modification. AlleleRetain and its supporting materials can be downloaded from https://sites.google.com/site/alleleretain/ or CRAN (http://cran.r-project.org).
保护遗传健康是物种保护的一个重要方面。等位基因多样性的保护尤为重要,因为它为适应提供了能力,从而使长期的种群生存能力成为可能。对于具有复杂人口统计学和生活史特征的实际种群,很难预测下一代的等位基因保留情况,因此我们开发了一种计算机模型来模拟小种群中的等位基因保留。AlleleRetain 是一个基于个体的模型,用 r 语言实现,可以用来评估在具有重叠世代的小型动物种群中保护等位基因多样性的管理选项。AlleleRetain 弥补了类似现有软件的局限性,其源代码可免费用于进一步修改。AlleleRetain 及其支持材料可从以下网址下载:https://sites.google.com/site/alleleretain/ 或 CRAN(http://cran.r-project.org)。