Shaw Gary Y, Million Stephanie K
Kansas City University of Medicine and Biomedical Sciences, Kansas City, MO 64086, USA.
Case Rep Otolaryngol. 2012;2012:814696. doi: 10.1155/2012/814696. Epub 2012 Aug 9.
Benign intracranial hypertension (BIH) (also known as pseudotumor cerebri and empty sella syndrome) remains a diagnostic challenge to most physicians. The modified Dandy criteria consist of, the classic findings of headache, pulsatile tinnitus, papilledema, and elevated cerebrospinal fluid (CSF) pressure, however, these are rarely collectively present in any one patient. Furthermore, these findings can wax and wane over time. Due to the nature of this disease, both signs and symptoms may be intermittent, making definitive diagnosis difficult. Newer imaging studies, particularly the magnetic resonance venogram (MRV) along with a constellation of correlative findings and associated diseases have given new impetus in the diagnosis, treatment, and pathophysiology of this disease. This has led the authors to offer modifications to the classic Dandy criteria. This report presents three representative cases of BIH highlighting many of the newer advances in both diagnosis and treatment of this perplexing disorder.
良性颅内高压(BIH)(也称为假性脑瘤和空蝶鞍综合征)对大多数医生来说仍然是一个诊断难题。改良的丹迪标准包括头痛、搏动性耳鸣、视乳头水肿和脑脊液(CSF)压力升高这些典型表现,然而,这些表现很少在任何一位患者身上同时出现。此外,这些表现会随时间波动。由于这种疾病的性质,体征和症状可能都是间歇性的,这使得明确诊断变得困难。更新的影像学检查,尤其是磁共振静脉血管造影(MRV)以及一系列相关发现和伴发疾病,为该疾病的诊断、治疗和病理生理学带来了新的推动力。这促使作者对经典的丹迪标准提出修改建议。本报告介绍了三例BIH的典型病例,突出了这种复杂疾病在诊断和治疗方面的许多新进展。