Department of Obstetrics and Gynaecology, Southern Clinical School, Monash University, Melbourne, VIC, Australia.
Med J Aust. 2012 Sep 3;197(5):278-81. doi: 10.5694/mja12.10125.
To determine if maternal country of birth is associated with the risk of antepartum stillbirth in late pregnancy.
DESIGN, SETTING AND PARTICIPANTS: Retrospective cross-sectional study of all singleton births at 37-42 weeks' gestation, excluding those with congenital abnormalities and intrapartum stillbirths, between 1 June 2001 and 31 May 2011 at Southern Health, a large metropolitan maternity service in Melbourne, Australia.
Rate of late-pregnancy antepartum stillbirth, analysed by maternal country of birth.
Among 44 326 births, there was a significant difference in the stillbirth rate by maternal country of birth (P < 0.001). The rate of stillbirth per 1000 births was 1.48 among Australian-born women, 3.55 among South Asian-born women and 1.06 among South-East-East Asian-born women. Women born in South Asia were 2.4 (95% CI, 1.4-4.0) times more likely to have a late-pregnancy stillbirth than women born in Australia (P < 0.001). There was no significant difference between women born in Australia and women born in South-East-East Asia (P = 0.34). Adjusting for potential confounding factors, South Asian maternal birth remained an independent risk factor for stillbirth (adjusted odds ratio, 2.5; 95% CI, 1.3-5.1; P = 0.009).
Women born in South Asia have an increased risk of antepartum stillbirth in late pregnancy, compared with other women. This observation may have implications for the delivery of pregnancy care in Australia.
确定产妇的出生国是否与妊娠晚期产前死胎的风险相关。
设计、地点和参与者:这是一项回顾性的横断研究,研究对象为 2001 年 6 月 1 日至 2011 年 5 月 31 日期间在澳大利亚墨尔本一个大型都会妇产服务机构 Southern Health 分娩的所有 37-42 周妊娠的单胎妊娠,排除了先天性异常和产时死胎。
按产妇出生国分析的妊娠晚期产前死胎发生率。
在 44326 例分娩中,产妇的出生国不同,死胎发生率存在显著差异(P<0.001)。每 1000 例活产的死胎率为澳大利亚出生的女性 1.48,南亚出生的女性 3.55,东南亚出生的女性 1.06。南亚出生的女性发生妊娠晚期死胎的风险比澳大利亚出生的女性高 2.4 倍(95%CI,1.4-4.0)(P<0.001)。澳大利亚出生的女性与东南亚出生的女性之间没有显著差异(P=0.34)。调整潜在混杂因素后,南亚产妇出生仍然是死胎的独立危险因素(调整后的比值比,2.5;95%CI,1.3-5.1;P=0.009)。
与其他女性相比,南亚出生的女性在妊娠晚期发生产前死胎的风险增加。这一观察结果可能对澳大利亚提供妊娠保健服务产生影响。