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无风湿性疾病或结核感染的类风湿结节形成:病例报告及文献复习。

Rice body formation without rheumatic disease or tuberculosis infection: a case report and literature review.

机构信息

Department of Pathology, Saint Barnabas Medical Center, Livingston, NJ 07039, USA.

出版信息

Clin Rheumatol. 2012 Dec;31(12):1753-6. doi: 10.1007/s10067-012-2063-8. Epub 2012 Sep 2.

Abstract

Rice body formation is an uncommon inflammatory disorder associated with systemic disorders such as rheumatoid arthritis and tuberculosis infection. The pathophysiology of rice bodies is poorly understood. We describe a case of rice body formation in a 51-year-old male who presented with pain and swelling of the left wrist. The patient had no previous history of rheumatic disease, joint trauma, or infectious disease. He underwent a radical tenosynovectomy and had immediate improvement of symptoms. Despite extensive evaluation, the etiology of the rice bodies could not be identified. An increasing number of case reports have described rice body formation without a known cause suggesting an alternative, unidentified method of pathogenesis. We describe a unique case of rice body formation and a review of the literature with emphasis on theories of pathogenesis, diagnostic methods, and treatment.

摘要

米粒体形成是一种罕见的炎症性疾病,与类风湿关节炎和结核感染等全身疾病有关。米粒体的病理生理学机制尚未完全清楚。我们描述了一例 51 岁男性患者,其因左腕部疼痛和肿胀就诊。该患者既往无风湿性疾病、关节创伤或传染病病史。他接受了彻底的腱鞘切除术,症状立即得到改善。尽管进行了广泛的评估,但仍无法确定米粒体的病因。越来越多的病例报告描述了无明确病因的米粒体形成,提示存在另一种未被识别的发病机制。我们描述了一例独特的米粒体形成病例,并对文献进行了复习,重点介绍了发病机制、诊断方法和治疗的理论。

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