Melicilamide A：来自白饭树的一种新型神经酰胺。

Melicilamide A: a new ceramide from Milicia excelsa.

机构信息

Department of Chemistry, Universität Paderborn, Warburger Straβe 100, 33098 Paderborn, Germany.

出版信息

Nat Prod Res. 2013;27(14):1246-9. doi: 10.1080/14786419.2012.724416. Epub 2012 Sep 11.

DOI:10.1080/14786419.2012.724416

Abstract

This article deals with a phytochemical investigation of Melicia excelsa from which melicilamide A (1), a new ceramide has been isolated. Its structure was determined by comprehensive analyses of its (1)H- and (13)C-NMR, COSY, HMQC and HMBC spectroscopic, EI-MS and ESI-MS data. The remaining one known compound was identified as β-sitosterol glucopyranoside.

摘要

本文对 Melicia excelsa 进行了植物化学研究，从中分离得到了一种新的神经酰胺 melicilamide A（1）。通过对其（1）H-NMR、（13）C-NMR、COSY、HMQC 和 HMBC 波谱、EI-MS 和 ESI-MS 数据的综合分析，确定了其结构。剩余的一种已知化合物被鉴定为β-谷甾醇葡萄糖苷。