Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
Neurourol Urodyn. 2013 Jun;32(5):424-7. doi: 10.1002/nau.22314. Epub 2012 Sep 12.
To determine the construct validity of an instrument to measure neuropathic pain in women with bladder pain syndrome (BPS). Our hypothesis is that neuropathic, bladder, and bowel pain represent different constructs in women with BPS.
Secondary planned analysis of a prospective cross-sectional study of 150 women with BPS. The relationship between neuropathic pain, urinary, and bowel symptoms was assessed.
The correlation of the total neuropathic pain score with total urinary and bowel symptom scores was low to moderate (r = 0.28-0.49). The correlation of specific neuropathic pain items with bladder and bowel pain was also low to moderate (r = 0.12-0.36). Women with neuropathic pain had significantly higher scores for urinary urgency, bladder pain, abdominal pain, diarrhea, and constipation than women with non-neuropathic pain (all P < 0.0001).
Somatosensory neuropathic pain and "visceral" bladder and bowel pain represent separate but related constructs in women with BPS.
确定一种用于测量膀胱疼痛综合征(BPS)女性神经性疼痛的工具的结构效度。我们的假设是,神经性疼痛、膀胱疼痛和肠痛在 BPS 女性中代表不同的结构。
对 150 名 BPS 女性的前瞻性横断面研究进行二次计划分析。评估神经性疼痛、尿和肠症状之间的关系。
总的神经性疼痛评分与总尿和肠症状评分之间的相关性为低到中度(r=0.28-0.49)。特定神经性疼痛项目与膀胱和肠痛的相关性也为低到中度(r=0.12-0.36)。有神经性疼痛的女性在尿急、膀胱疼痛、腹痛、腹泻和便秘方面的评分明显高于无神经性疼痛的女性(均 P<0.0001)。
躯体感觉神经性疼痛和“内脏”膀胱和肠痛在 BPS 女性中代表不同但相关的结构。