Yamashita Y, Maki A, Koizumi H
J Biomed Opt. 1999 Oct;4(4):414-7. doi: 10.1117/1.429940.
We have developed a 24-channel simultaneous measurement system for optical topography that noninvasively obtains dynamic images of brain activity using near-infrared light. To evaluate the system performance, we utilized a dynamic phantom containing a rotating absorber in a cylindrical scattering medium. In this system, eight incident and eight detecting optical fibers are arranged alternately at square lattice points on the phantom. The phantom is illuminated with light of two wavelengths (780 and 830 nm) from each incident fiber. Reflected light is received by the detecting fibers, each of which is connected to an avalanche photodiode. Multiple light intensity modulation and lock-in detection are used to enable highly sensitive measurement with negligible cross talk for multichannel measurement. In the phantom measurement, we obtained topographic dynamic images of the absorber rotating in the medium with a temporal resolution of 0.5 s over a measurement area of 90 mm×90 mm. © 1999 Society of Photo-Optical Instrumentation Engineers.
我们开发了一种用于光学地形图的24通道同步测量系统,该系统使用近红外光无创获取大脑活动的动态图像。为了评估系统性能,我们使用了一个动态体模,该体模在圆柱形散射介质中包含一个旋转吸收体。在该系统中,八根入射光纤和八根检测光纤交替排列在体模上的方形晶格点处。从每根入射光纤用两种波长(780和830nm)的光照射体模。反射光由检测光纤接收,每根检测光纤都连接到一个雪崩光电二极管。采用多重光强调制和锁相检测,实现多通道测量时具有高灵敏度且串扰可忽略不计的测量。在体模测量中,我们在90mm×90mm的测量区域内以0.5s的时间分辨率获得了吸收体在介质中旋转的地形图动态图像。©1999美国光电仪器工程师协会。