Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, AL, USA.
Am J Obstet Gynecol. 2013 Mar;208(3):169-75. doi: 10.1016/j.ajog.2012.09.007. Epub 2012 Sep 14.
Persistence of human papillomavirus (HPV) infection is necessary for the development of cervical cancer. Additionally, infection with HPV is implicated in the majority of cases of other genital tract malignancies including vulvar, penile, and vaginal cancer. HPV testing and vaccination are a routine part of obstetrical/gynecological clinical practice. With an enhanced public awareness of HPV infections, many patients turn to their obstetricians/gynecologists with questions about transmission, testing, and prevention. In this review, we will discuss the biology of HPV, epidemiology of disease, methods and indications for testing, and vaccination strategies.
人乳头瘤病毒(HPV)感染的持续存在是宫颈癌发展的必要条件。此外,HPV 感染与外阴、阴茎和阴道癌等大多数生殖道恶性肿瘤的发生有关。HPV 检测和疫苗接种是妇产科临床实践的常规内容。随着公众对 HPV 感染认识的提高,许多患者向妇产科医生咨询有关传播、检测和预防的问题。在这篇综述中,我们将讨论 HPV 的生物学、疾病的流行病学、检测方法和适应症以及疫苗接种策略。