Forrester Mathias B
Epidemiology and Disease Surveillance Unit, Texas Department of State Health Services, Austin, TX 78756, USA.
Pediatr Emerg Care. 2012 Oct;28(10):985-9. doi: 10.1097/PEC.0b013e31826c9a97.
This study describes the pattern of adolescent synthetic cannabinoid exposures reported to a large statewide poison center system.
Synthetic cannabinoid exposures among patients younger than 20 years reported to Texas poison centers during January 2010 to June 2011 were identified. The distribution of exposures by various demographic and clinical factors was determined.
For 305 adolescent exposures, the mean age was 16.7 years (range, 12-19 y). The exposure was by inhalation in 77.4% of the cases, and 72.1% involved males. The exposure site was the patient's own residence in 70.5% of the cases, and a health care facility was the caller site in 68.9%. The patient was already at or en route to a health care facility in 80.3% of the cases, and the medical outcome was serious in 61.0%. The most frequently reported adverse clinical effects were tachycardia (41.6%), drowsiness/lethargy (24.3%), agitation/irritability (16.4%), vomiting (13.1%), hallucinations/delusions (11.5%), nausea (8.5%), confusion (8.2%), hypertension (7.5%), chest pain (6.9%), and dizziness/vertigo (5.2%).
Adolescent synthetic cannabinoid exposures reported to Texas poison centers were more likely to involve inhalation. The adolescents were more likely to be male. The exposures more often occurred at the patient's own residence and managed at a health care facility with a serious outcome. This pattern of exposures was similar to that observed among adults.
本研究描述了向一个大型全州中毒控制中心系统报告的青少年合成大麻素暴露情况。
确定2010年1月至2011年6月期间向德克萨斯州中毒控制中心报告的20岁以下患者的合成大麻素暴露情况。确定了各种人口统计学和临床因素导致的暴露分布。
在305例青少年暴露病例中,平均年龄为16.7岁(范围为12 - 19岁)。77.4%的病例通过吸入暴露,72.1%涉及男性。70.5%的病例暴露地点为患者自己的住所,68.9%的病例呼叫地点为医疗机构。80.3%的病例患者已在或正在前往医疗机构的途中,61.0%的病例医疗结果严重。最常报告的不良临床影响为心动过速(41.6%)、嗜睡/昏睡(24.3%)、激动/易怒(16.4%)、呕吐(13.1%)、幻觉/妄想(11.5%)、恶心(8.5%)、意识模糊(8.2%)、高血压(7.5%)、胸痛(6.9%)和头晕/眩晕(5.2%)。
向德克萨斯州中毒控制中心报告的青少年合成大麻素暴露更可能涉及吸入。青少年更可能为男性。暴露更常发生在患者自己的住所,并在医疗机构进行处理,结果严重。这种暴露模式与在成年人中观察到的相似。