Department Obstetrics & Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Neurourol Urodyn. 2013 Jun;32(5):455-9. doi: 10.1002/nau.22327. Epub 2012 Sep 28.
This study focused on the changes in urinary incontinence (UI) rates pre- and postoperatively and identified risk factors which predict the presence of symptoms of urgency urinary incontinence (UUI) or stress urinary incontinence (SUI) after surgery for pelvic organ prolapse (POP) without concomitant or previous anti-incontinence surgery.
All consecutive women who underwent POP surgery without concomitant or previous anti-incontinence surgery in the years 2004-2010 were included. Assessments were performed preoperatively and at 1-year follow-up, including pelvic organ prolapse quantification score and a standardized urogynecological questionnaire (Urogenital Distress Inventory, UDI). Primary outcome of this study was stress and/or urgency UI postoperatively. Furthermore, this study measured the improvement or worsening of UI following surgery using the UDI. Univariable- and multivariable logistic regression with forward selection procedure was used to identify the risk factors.
Nine hundred seven patients were included. De novo SUI appeared in 22% and de novo UUI occurred in 21% of the women. At 1-year 42% were cured for UUI and 39% were recovered from SUI by POP surgery alone. The best predictor for the occurrence of postoperative SUI or UUI was the presence of preoperative SUI or UUI. BMI and chronic obstructive pulmonary disease (COPD) were identified as independent risk factors for postoperative SUI. A recurrence in the anterior compartment protected against SUI postoperatively.
Preoperative SUI or UUI is the most important predictor of SUI and UUI postoperatively. BMI and COPD were identified as important risk factors for SUI.
本研究重点关注盆腔器官脱垂(POP)手术前后尿失禁(UI)发生率的变化,并确定预测术后急迫性尿失禁(UUI)或压力性尿失禁(SUI)症状存在的风险因素,这些患者无合并或先前的抗失禁手术。
本研究纳入了 2004 年至 2010 年期间行 POP 手术而无合并或先前抗失禁手术的所有连续女性患者。术前和 1 年随访时进行评估,包括盆腔器官脱垂定量评分和标准化尿失禁问卷(尿失禁困扰量表,UDI)。本研究的主要结局为术后压力性和/或急迫性尿失禁。此外,本研究使用 UDI 测量术后 UI 的改善或恶化情况。采用向前选择法进行单变量和多变量逻辑回归,以确定风险因素。
本研究纳入了 907 例患者。新发 SUI 发生率为 22%,新发 UUI 发生率为 21%。术后 1 年,42%的患者 UUI 治愈,39%的患者单独行 POP 手术恢复 SUI。术前 SUI 或 UUI 是术后发生 SUI 或 UUI 的最佳预测因素。BMI 和慢性阻塞性肺疾病(COPD)被确定为术后 SUI 的独立危险因素。前盆腔器官的复发可预防术后 SUI。
术前 SUI 或 UUI 是术后 SUI 和 UUI 的最重要预测因素。BMI 和 COPD 被确定为 SUI 的重要危险因素。