McConkey Sandra E, Walker Susan, Adams Cathy
Biomedical Sciences, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island CIA 4P3, Canada.
Can Vet J. 2012 Apr;53(4):391-4.
Two cases that involve drug compounding errors are described. One dog exhibited increased seizure activity due to a compounded, flavored phenobarbital solution that deteriorated before the expiration date provided by the compounder. The other dog developed clinical signs of hyperkalemia and bromine toxicity following a 5-fold compounding error in the concentration of potassium bromide (KBr).
描述了两起涉及药物配制错误的案例。一只狗因配制的调味苯巴比妥溶液在配制者提供的有效期前变质而出现癫痫发作活动增加。另一只狗在溴化钾(KBr)浓度出现5倍的配制错误后出现高钾血症和溴中毒的临床症状。