Ozyurt Kemal, Colgecen Emine, Baykan Halit, Ozturk Perihan, Ozkose Mehmet
Department of Dermatology, Medicine Faculty, Sutcu Imam University, 46100 Kahramanmaras, Turkey.
ScientificWorldJournal. 2012;2012:197139. doi: 10.1100/2012/197139. Epub 2012 Sep 17.
Recent published studies evaluating the long-pulsed 1064 nm Nd:YAG laser for superficial cutaneous vascular lesions have limited subjects and optimal treatment parameters have not been established. To determine the efficacy and safety of the long-pulsed 1064 nm Nd:YAG laser on superficial cutaneus vascular lesions and analyse retrospectively our experience of a 3-year period are the aims of this study. Over the 3-year period, 255 patients were treated [189 female and 66 male; median age 35 (range 7-65) years; Fitzpatrick skin types II-V]. Twenty-six patients with spider angioma, 130 with facial telangiectasia, and 99 with leg telangiectasia were treated. A long-pulsed 1064 nm Nd:YAG laser was used. A test dose was performed at the initial consultation and thereafter patients were reviewed and treated at 4-week intervals for 5 months. Of those patients who completed treatment and followup, 26/26 (100%) of spider angiomas, 125/130 (97%) of facial telangiectasia, and 80/99 (80,8%) of leg telangiectasia markedly improved or cleared. We suggest that the long pulsed Nd:YAG laser is a safe and effective treatment for common superficial cutaneous vascular lesions. However, it is not the first choise to use to treat superficial vessels on the face where depth is not the concern.
近期发表的评估长脉冲1064纳米钕:钇铝石榴石激光治疗浅表皮肤血管病变的研究,受试者数量有限,且尚未确定最佳治疗参数。本研究的目的是确定长脉冲1064纳米钕:钇铝石榴石激光治疗浅表皮肤血管病变的疗效和安全性,并回顾性分析我们3年期间的经验。在这3年期间,共治疗了255例患者[189例女性和66例男性;中位年龄35岁(范围7 - 65岁);皮肤类型为菲茨帕特里克II - V型]。治疗了26例蜘蛛状血管瘤患者、130例面部毛细血管扩张患者和99例腿部毛细血管扩张患者。使用了长脉冲1064纳米钕:钇铝石榴石激光。在初次会诊时进行了试验剂量,此后患者每4周复诊并治疗一次,持续5个月。在完成治疗和随访的患者中,26例蜘蛛状血管瘤患者中的26例(100%)、130例面部毛细血管扩张患者中的125例(97%)以及99例腿部毛细血管扩张患者中的80例(80.8%)明显改善或消退。我们认为长脉冲钕:钇铝石榴石激光是治疗常见浅表皮肤血管病变的一种安全有效的方法。然而,对于面部浅表血管的治疗,在不考虑深度的情况下,它并非首选。