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一项关于颅缝早闭手术修复的全国性研究。

A national study on craniosynostosis surgical repair.

作者信息

Nguyen Christine, Hernandez-Boussard Tina, Khosla Rohit K, Curtin Catherine M

出版信息

Cleft Palate Craniofac J. 2013 Sep;50(5):555-60. doi: 10.1597/11-324. Epub 2012 Oct 2.

Abstract

Objective : Our study aimed to use national data to assess the perioperative outcomes of craniosynostosis surgical repair. Design : Data were obtained from the Agency for Healthcare Research and Quality Healthcare Cost and Utilization Project Kids Inpatient Database from 1997, 2000, 2003, and 2006. Setting : Community hospitals in the United States. Patients : The cohort was identified using the ICD-9-CM procedure codes for craniosynostosis surgical repair (2.01, 2.03, 2.04, 2.06). Main Outcome Measures(s) : We determined patient and hospital characteristics. We clustered patients by age group (<7 months, 7 to 12 months, 1 to 3 years) and assessed mortality, comorbidities, mean length of stay (LOS), and total charge. We performed logistic regression with our dependent variable being longer average hospital stay: LOS > 4.2 days. Results : We found 3426 patients. Average age at the time of surgery was 181 days (SD 84). Average length of stay was 4.2 days. The majority of the patients were boys (66%), white (71%), and insured (93%). Nearly all patients underwent surgery in a teaching hospital (98%) in urban centers (99%). Approximately 10% of patients experienced an acute complication, most commonly hemorrhages or hematomas and airway or respiratory failure. Patients ages 1 to 3 years had the highest rates of comorbidities and a longer LOS. Mortality rate was <1%. Conclusions : Craniosynostosis surgery is safe with low rates of mortality and acute complications. LOS >4.2 appears to be associated more with comorbidities than with complications. Higher rates of comorbidities and LOS >4.2 days for patients age 1 to 3 years warrant addition research to assess potential barriers to care.

摘要

目的

我们的研究旨在利用全国数据评估颅缝早闭手术修复的围手术期结局。

设计

数据来自医疗保健研究与质量机构的医疗保健成本和利用项目儿童住院数据库,时间为1997年、2000年、2003年和2006年。

地点

美国的社区医院。

患者

使用国际疾病分类第九版临床修订本(ICD-9-CM)中颅缝早闭手术修复的程序编码(2.01、2.03、2.04、2.06)确定队列。

主要结局指标

我们确定了患者和医院的特征。我们按年龄组(<7个月、7至12个月、1至3岁)对患者进行聚类,并评估死亡率、合并症、平均住院时间(LOS)和总费用。我们进行了逻辑回归,因变量为平均住院时间延长:LOS>4.2天。

结果

我们共找到3426名患者。手术时的平均年龄为181天(标准差84)。平均住院时间为4.2天。大多数患者为男孩(66%)、白人(71%)且有保险(93%)。几乎所有患者都在城市中心的教学医院(98%)接受手术(99%)。约10%的患者发生急性并发症,最常见的是出血或血肿以及气道或呼吸衰竭。1至3岁的患者合并症发生率最高,住院时间也更长。死亡率<1%。

结论

颅缝早闭手术安全,死亡率和急性并发症发生率低。LOS>4.2天似乎更多与合并症而非并发症相关。1至3岁患者较高的合并症发生率和LOS>4.2天,需要进一步研究以评估潜在的护理障碍。

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