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1
Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300.
Angew Chem Int Ed Engl. 2012 Nov 5;51(45):11258-62. doi: 10.1002/anie.201206815. Epub 2012 Oct 8.
2
Total Syntheses of Lobaric Acid and Its Derivatives from the Antarctic Lichen Stereocaulon alpinum.
J Nat Prod. 2018 Jun 22;81(6):1460-1467. doi: 10.1021/acs.jnatprod.8b00227. Epub 2018 Jun 7.
3
Covalent Chemical Cochaperones of the p300/CBP GACKIX Domain.
Chembiochem. 2018 Sep 17;19(18):1907-1912. doi: 10.1002/cbic.201800173. Epub 2018 Sep 5.
4
The structural basis of protein acetylation by the p300/CBP transcriptional coactivator.
Nature. 2008 Feb 14;451(7180):846-50. doi: 10.1038/nature06546.
5
Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.
Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6078-83. doi: 10.1073/pnas.1119073109. Epub 2012 Apr 2.
6
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
Bioorg Med Chem. 2018 Dec 1;26(22):5845-5851. doi: 10.1016/j.bmc.2018.10.035. Epub 2018 Oct 28.
7
Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.
J Med Chem. 2016 Feb 25;59(4):1648-53. doi: 10.1021/acs.jmedchem.5b01719. Epub 2016 Jan 13.
8
Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors.
J Med Chem. 2016 Oct 13;59(19):8889-8912. doi: 10.1021/acs.jmedchem.6b00774. Epub 2016 Sep 27.
9
Probing the reaction coordinate of the p300/CBP histone acetyltransferase with bisubstrate analogs.
Bioorg Chem. 2011 Feb;39(1):42-7. doi: 10.1016/j.bioorg.2010.10.004. Epub 2010 Oct 28.

引用本文的文献

1
Garcinolic Acid Distinguishes Between GACKIX Domains and Modulates Interaction Networks.
Chembiochem. 2023 Nov 2;24(21):e202300439. doi: 10.1002/cbic.202300439. Epub 2023 Sep 7.
2
Rational peptide design for inhibition of the KIX-MLL interaction.
Sci Rep. 2023 Apr 18;13(1):6330. doi: 10.1038/s41598-023-32848-2.
3
Peptide Tethering: Pocket-Directed Fragment Screening for Peptidomimetic Inhibitor Discovery.
J Am Chem Soc. 2022 Jan 26;144(3):1198-1204. doi: 10.1021/jacs.1c09666. Epub 2022 Jan 14.
4
Norstictic Acid Is a Selective Allosteric Transcriptional Regulator.
J Am Chem Soc. 2021 Jun 30;143(25):9297-9302. doi: 10.1021/jacs.1c03258. Epub 2021 Jun 17.
6
Unexpected specificity within dynamic transcriptional protein-protein complexes.
Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27346-27353. doi: 10.1073/pnas.2013244117. Epub 2020 Oct 19.
7
Selective Modulation of Dynamic Protein Complexes.
Cell Chem Biol. 2020 Aug 20;27(8):986-997. doi: 10.1016/j.chembiol.2020.07.019. Epub 2020 Aug 11.
8
Collision-Induced Unfolding Reveals Unique Fingerprints for Remote Protein Interaction Sites in the KIX Regulation Domain.
J Am Soc Mass Spectrom. 2019 Jan;30(1):94-102. doi: 10.1007/s13361-018-2043-6. Epub 2018 Aug 22.
9
Covalent Chemical Cochaperones of the p300/CBP GACKIX Domain.
Chembiochem. 2018 Sep 17;19(18):1907-1912. doi: 10.1002/cbic.201800173. Epub 2018 Sep 5.
10
Dual Labeling of the CBP/p300 KIX Domain for F NMR Leads to Identification of a New Small-Molecule Binding Site.
Chembiochem. 2018 May 4;19(9):963-969. doi: 10.1002/cbic.201700686. Epub 2018 Apr 6.

本文引用的文献

1
Fine-tuning multiprotein complexes using small molecules.
ACS Chem Biol. 2012 Aug 17;7(8):1311-20. doi: 10.1021/cb300255p. Epub 2012 Jul 23.
2
Direct and selective small-molecule activation of proapoptotic BAX.
Nat Chem Biol. 2012 Jul;8(7):639-45. doi: 10.1038/nchembio.995. Epub 2012 May 27.
4
Conformational control of the binding of the transactivation domain of the MLL protein and c-Myb to the KIX domain of CREB.
PLoS Comput Biol. 2012;8(3):e1002420. doi: 10.1371/journal.pcbi.1002420. Epub 2012 Mar 15.
5
Small-molecule stabilization of protein-protein interactions: an underestimated concept in drug discovery?
Angew Chem Int Ed Engl. 2012 Feb 27;51(9):2012-8. doi: 10.1002/anie.201107616. Epub 2012 Feb 3.
6
Antioxidant activity of some lichen metabolites.
Nat Prod Res. 2011 Nov;25(19):1827-37. doi: 10.1080/14786419.2010.529546. Epub 2011 Jun 30.
7
Caught in the act: covalent cross-linking captures activator-coactivator interactions in vivo.
ACS Chem Biol. 2011 Dec 16;6(12):1321-6. doi: 10.1021/cb200308e. Epub 2011 Nov 14.
8
Thermodynamics-based drug design: strategies for inhibiting protein-protein interactions.
Future Med Chem. 2011 Jul;3(9):1129-37. doi: 10.4155/fmc.11.81.
9
The role of CREB signaling in Alzheimer's disease and other cognitive disorders.
Rev Neurosci. 2011;22(2):153-69. doi: 10.1515/RNS.2011.018.
10
Transient-state kinetic analysis of transcriptional activator·DNA complexes interacting with a key coactivator.
J Biol Chem. 2011 May 6;286(18):16238-45. doi: 10.1074/jbc.M110.207589. Epub 2011 Feb 12.

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