Department of Physical Medicine and Rehabilitation, China Medical University Beigang Hospital, Yunlin, Taiwan, ROC.
Cell Transplant. 2013;22(4):677-84. doi: 10.3727/096368912X655118. Epub 2012 Oct 8.
Tendon injury may occur suddenly or progressively, and can be divided into tendon rupture or tendinopathy based on the severity of injury. It is frequently found in professional or nonprofessional people who are making repetitive movements. In aged people, tendon degeneration becomes obvious; their tendon injuries are then frequently evident. No effective therapies for tendon injury are currently available. In this article, we review the tendon structure, mechanisms of tendon injury, and tendon healing process. More importantly, cell-based therapies for tendon injury are fully addressed, which will play an important role for tendon therapy in the near future.
肌腱损伤可能是突然发生的,也可能是逐渐发生的,根据损伤的严重程度,可分为肌腱断裂或肌腱病。它经常发生在进行重复运动的专业或非专业人士身上。在老年人中,肌腱退化变得明显,他们的肌腱损伤也经常出现。目前尚无有效的肌腱损伤治疗方法。本文综述了肌腱结构、肌腱损伤机制和肌腱愈合过程。更重要的是,全面介绍了基于细胞的肌腱损伤治疗方法,这将在不久的将来为肌腱治疗发挥重要作用。