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成人阅读障碍者除语音处理缺陷外:空间问题解决的功能性磁共振成像激活模式异常

Beyond phonological processing deficits in adult dyslexics: atypical FMRI activation patterns for spatial problem solving.

作者信息

Olulade Olumide A, Gilger Jeffrey W, Talavage Thomas M, Hynd George W, McAteer Carole I

机构信息

Center for the Study of Learning, Georgetown University Medical Center, Washington, District of Columbia, USA.

出版信息

Dev Neuropsychol. 2012;37(7):617-35. doi: 10.1080/87565641.2012.702826.

Abstract

It is unclear the extent to which neurodevelopmental differences observed in reading disabled individuals are limited to traditional language processing areas. Some have suggested atypical processing of complex spatial problems in these individuals. Hitherto, research on this question has been limited to behavioral studies, yielding mixed results. Absence of related imaging studies is in stark contrast to the plethora examining functional neurology for verbal tasks. This study uses functional magnetic resonance imaging (fMRI) to examine how adult dyslexics perform when analyzing complex spatial material unrelated to the reading of text. We observed atypical functional neurology during spatial problem solving, which was not observed behaviorally.

摘要

目前尚不清楚在阅读障碍个体中观察到的神经发育差异在多大程度上局限于传统语言处理区域。一些人认为这些个体在处理复杂空间问题时存在非典型加工。迄今为止,关于这个问题的研究仅限于行为研究,结果不一。缺乏相关的影像学研究与大量针对语言任务的功能神经学研究形成了鲜明对比。本研究使用功能磁共振成像(fMRI)来检查成年诵读困难者在分析与文本阅读无关的复杂空间材料时的表现。我们在空间问题解决过程中观察到了非典型的功能神经学现象,而这在行为上并未观察到。

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