因使用低剂量非那雄胺导致的继发性不孕。
Secondary infertility due to use of low-dose finasteride.
机构信息
Department of Urology, Faculty of Medicine, Rumi University, Aksinne Mah, Esmetaş Sok, No: 16, 42040 Meram, Konya, Turkey.
出版信息
Int Urol Nephrol. 2013 Feb;45(1):83-5. doi: 10.1007/s11255-012-0315-9. Epub 2012 Oct 16.
Herein, we present an unusual case of secondary infertility after prolonged use of low-dose finasteride for androgenetic alopecia in a 40-year-old man. We detected sperm DNA damage in the patient. Despite such a long-term use, we observed that impairment in semen parameters and sperm DNA fragmentation index regressed after the drug was discontinued. Consequently, pregnancy occurred and resulted in live birth.
在此，我们报告了一例罕见的病例，一名 40 岁男性因雄激素性脱发长期使用低剂量非那雄胺后出现继发性不孕。我们检测到患者的精子 DNA 损伤。尽管使用时间如此之长，但我们观察到，停药后精液参数和精子 DNA 碎片化指数的损害有所恢复。结果，患者成功妊娠并分娩活婴。
Zotero 插件