滴注含有苯扎氯铵的滴鼻剂后发生过敏反应。
Anaphylactic reaction following administration of nose drops containing benzalkonium chloride.
机构信息
Department of Otorhinolaryngology-Head and Neck Surgery, University of Erlangen, Germany.
出版信息
Head Face Med. 2012 Oct 18;8:29. doi: 10.1186/1746-160X-8-29.
Abstract
We describe a case of anaphylactic reaction in a 46-year-old female post application of decongestant nose drops containing benzalkonium chloride (BAC). With some latency, the patient complained of cough, dyspnea, sensation of heat, croakiness and pruritus. Since she showed all of these symptoms, typical of an anaphylactic reaction, we proceeded some weeks later with a prick test with solutions containing BAC, a cationic surfactant commonly used as an antibacterial preservative in many medical solutions. The prick test was positive, confirming the assumption of a hypersensitive reaction to BAC.
摘要
我们描述了一例 46 岁女性在使用含有苯扎氯铵（BAC）的减充血滴鼻剂后的过敏反应病例。在一定潜伏期后，患者出现咳嗽、呼吸困难、灼热感、声音嘶哑和瘙痒等症状。由于这些症状均为典型的过敏反应，数周后我们对患者进行了 BAC 点刺试验，BAC 是一种阳离子表面活性剂，常用于许多医疗溶液中的抗菌防腐剂。点刺试验呈阳性，证实了对 BAC 过敏反应的假设。
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