在白内障术前患者中，使用 Oculyzer II 和 WaveLight OB820 测量的中央角膜厚度、前房深度和角膜曲率之间的相关性。
Correlation between central corneal thickness, anterior chamber depth, and corneal keratometry as measured by Oculyzer II and WaveLight OB820 in preoperative cataract surgery patients.
机构信息
Laservision Eye Institute, Athens, Greece.
出版信息
J Refract Surg. 2012 Dec;28(12):895-900. doi: 10.3928/1081597X-20121005-07. Epub 2012 Oct 22.
PURPOSE
To compare and correlate central corneal thickness (CCT), anterior chamber depth (ACD), and keratometric (flat and steep K) measurements using two anterior segment imaging methods, a Scheimpflug camera system (Oculyzer II [Oculus Optikgeräte GmbH]) and a partial coherence biometry system (WaveLight OB820 [Alcon Laboratories Inc]) in eyes undergoing cataract surgery.
METHODS
Ninety patients (mean age: 66±13 years [range: 32 to 88 years]) underwent preoperative measurement of CCT, ACD, and keratometric measurements by Scheimpflug tomography (Oculyzer II) and optical low coherence reflectometry (WaveLight OB820). Interdevice agreement and correlation between the two techniques were assessed.
RESULTS
All measurements were highly correlated and showed no clinically significant difference between methods. Mean CCT was 554.21±39.07 μm and 546.59±37.75 μm for the Oculyzer II and WaveLight OB820, respectively (R²=0.9268). Mean ACD was 2.63±0.44 mm and 2.63±0.43 mm for the Oculyzer II and WaveLight OB820, respectively (R(2)=0.9488). The principal meridian keratometric values were also highly correlated. Mean flat K was 42.88±1.50 diopters (D) and 42.96±1.40 D for the Oculyzer II and WaveLight OB820, respectively (R²=0.8741). Mean steep K was 44.08±1.79 D and 44.26±1.95 D for the Oculyzer II and WaveLight OB820, respectively (R(2)=0.9159).
CONCLUSIONS
Our data show that the Oculyzer II and WaveLight OB820 provide measurements that are in agreement with published values for CCT and ACD in patients. Excellent agreement for CCT and ACD was found between the two devices, as demonstrated by a high degree of correlation and linearity, in addition to minimal bias. Thus, CCT, ACD, and K measurements by these instruments can both be used in clinical preparation, and their agreement is an ensuring precision factor for cataract and refractive surgeons.
目的
比较和关联两种眼前段成像方法（Scheimpflug 相机系统[Oculus Optikgeräte GmbH]和部分相干生物测量系统[WaveLight OB820[Alcon Laboratories Inc.]]）测量的中央角膜厚度（CCT）、前房深度（ACD）和角膜曲率（平 K 和陡 K），以评估其在白内障手术患者中的应用。
方法
90 名患者（平均年龄：66±13 岁[范围：32 至 88 岁]）接受术前 Scheimpflug 断层扫描（Oculyzer II）和光学低相干反射测量（WaveLight OB820）的 CCT、ACD 和角膜曲率测量。评估两种技术之间的设备间一致性和相关性。
结果
所有测量值均高度相关，两种方法之间无临床显著差异。Oculyzer II 组的平均 CCT 为 554.21±39.07μm，WaveLight OB820 组为 546.59±37.75μm（R²=0.9268）。Oculyzer II 组的平均 ACD 为 2.63±0.44mm，WaveLight OB820 组为 2.63±0.43mm（R²=0.9488）。主经线角膜曲率值也高度相关。Oculyzer II 组平均平 K 为 42.88±1.50 屈光度（D），WaveLight OB820 组为 42.96±1.40D（R²=0.8741）。Oculyzer II 组平均陡 K 为 44.08±1.79D，WaveLight OB820 组为 44.26±1.95D（R²=0.9159）。
结论
我们的数据表明，Oculyzer II 和 WaveLight OB820 提供的 CCT 和 ACD 测量值与已发表的患者值一致。两种设备之间 CCT 和 ACD 的一致性非常好，表现为高度相关和线性，并且偏差最小。因此，这些仪器的 CCT、ACD 和 K 测量值均可用于临床准备，其一致性是白内障和屈光外科医生确保精度的一个因素。
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