人类微生物组学。
Human microbiomics.
机构信息
Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, 625 021 India.
出版信息
Indian J Microbiol. 2010 Mar;50(1):109-12. doi: 10.1007/s12088-010-0034-9. Epub 2010 Apr 29.
Abstract
The sequencing of the human genome has driven the study of human biology in a significant way and enabled the genome-wide study to elucidate the molecular basis of complex human diseases. Recently, the role of microbiota on human physiology and health has received much attention. The influence of gut microbiome (the collective genomes of the gut microbiota) in obesity has been demonstrated, which may pave the way for new prophylactic and therapeutic strategies such as bacteriotherapy. The significance and recent understandings in the area of "human microbiomics" are discussed here.
摘要
人类基因组测序以重大的方式推动了人类生物学的研究，并使全基因组研究能够阐明复杂人类疾病的分子基础。最近，微生物组对人类生理和健康的作用受到了广泛关注。肠道微生物组（肠道微生物群的集体基因组）在肥胖中的影响已经得到证实，这可能为新的预防和治疗策略（如细菌治疗）铺平道路。本文讨论了“人类微生物组学”领域的意义和最新认识。
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