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孤立性三尖瓣手术:不良结局和生存的预测因素。

Isolated tricuspid valve surgery: predictors of adverse outcome and survival.

机构信息

Anesthesiology and Cardiothoracic Surgery, Mount Sinai School of Medicine, New York, NY 10029, United States.

出版信息

Heart Lung Circ. 2013 Mar;22(3):211-20. doi: 10.1016/j.hlc.2012.09.006. Epub 2012 Oct 25.

Abstract

BACKGROUND

Isolated tricuspid valve surgery is a rare operation, for which outcomes are not well defined. We describe a single-centre experience with isolated tricuspid surgery, and an analysis of risk factors for adverse outcome and predictors of survival.

METHODS

Retrospective analysis of 56 consecutive adult patients undergoing isolated tricuspid valve surgery between November 1998 and November 2010 was performed.

RESULTS

Eight patients died in hospital (early mortality 14.2%). In comparison with tricuspid repair patients, tricuspid replacement patients required more intraoperative red cell blood transfusion (RBC>1 unit: p=0.033), platelet transfusion (p=0.051), and more postoperative ventilator support (p=0.023). Predictors of early (in hospital) mortality include advanced age (p=0.019) higher euroSCORE (p<0.001), transfusion of intraoperative red blood cells (p=0.005), and cryoprecipitate (p=0.014). Twenty-five patients (44.6%) reached the end-point of death. There was no statistical difference in early and late survival rates between repair and replacement groups.

CONCLUSIONS

Patients with isolated tricuspid valve surgery continue to be a high-risk group in cardiac surgery with unacceptable operative mortality and limited survival. There were no statistical differences in early and late outcomes between the isolated tricuspid valve repair versus replacement surgery. Timely referral to surgery before the onset of class 3 heart failure, malnutrition, renal dysfunction and age>60 years is recommended.

摘要

背景

孤立性三尖瓣手术是一种罕见的手术,其结果尚不清楚。我们描述了单一中心的孤立性三尖瓣手术经验,并分析了不良结果的危险因素和生存预测因素。

方法

回顾性分析了 1998 年 11 月至 2010 年 11 月期间连续 56 例接受孤立性三尖瓣手术的成年患者。

结果

8 例患者在院内死亡(早期死亡率为 14.2%)。与三尖瓣修复患者相比,三尖瓣置换患者需要更多的术中红细胞输血(RBC>1 单位:p=0.033)、血小板输血(p=0.051)和更长时间的呼吸机支持(p=0.023)。早期(院内)死亡率的预测因素包括年龄较大(p=0.019)、欧洲心脏手术风险评分较高(p<0.001)、术中红细胞输血(p=0.005)和冷沉淀输血(p=0.014)。25 例患者(44.6%)达到死亡终点。修复组和置换组在早期和晚期生存率方面无统计学差异。

结论

孤立性三尖瓣手术患者仍然是心脏手术中的高危人群,手术死亡率高,生存有限。孤立性三尖瓣修复与置换手术在早期和晚期结果方面无统计学差异。建议在出现 3 级心力衰竭、营养不良、肾功能障碍和年龄>60 岁之前及时转至手术治疗。

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