马哈拉施特拉邦西部健康人群血清脂质谱参考区间的评估。
Evaluation of reference intervals of serum lipid profile from healthy population in Western Maharashtra.
作者信息
Durgawale Pushpa, Patil Sangita, Shukla P S, Sontakke Ajit, Kakade Satish, Yadav Sunil
机构信息
Department of Biochemistry, Krishna Institute of Medical Sciences, Karad, Maharashtra India ; Department of Biochemistry, Krishna Institute of Medical Sciences Karad, 415110 Satara, Maharashtra India.
出版信息
Indian J Clin Biochem. 2009 Jan;24(1):30-5. doi: 10.1007/s12291-009-0005-2. Epub 2009 May 8.
Fasting samples of 914 subjects from healthy population were analyzed for total cholesterol, triglyceride and three major fractions of lipoproteins i.e. high-density lipoprotein cholesterol, low lipoprotein cholesterol and very low-density lipoprotein cholesterol. The values obtained were (in mg/dl) 165.7±30.2,88.36±31.2, 44.86±10.68, 101.66±29.8 and 18.11±7.35 respectively. When these subjects were grouped according to the age and sex, no appropriate differences were observed between most of the groups. Triglycerides were found to be low and HDL cholesterol was high in female when compared with male of similar age. Beyond age 40 years cholesterol level and low density lipoprotein cholesterol was found to be gradually increased in case of women. Minor difference was observed with dietary pattern. Present study suggests that clinical evaluation of patient should be made on the basis of these reference values for Western Maharashtra population.
对来自健康人群的914名受试者的空腹样本进行了总胆固醇、甘油三酯以及三种主要脂蛋白组分（即高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和极低密度脂蛋白胆固醇）的分析。所获得的值（以mg/dl为单位）分别为165.7±30.2、88.36±31.2、44.86±10.68、101.66±29.8和18.11±7.35。当根据年龄和性别对这些受试者进行分组时，大多数组之间未观察到适当的差异。与年龄相仿的男性相比，发现女性的甘油三酯水平较低，高密度脂蛋白胆固醇水平较高。40岁以上的女性，胆固醇水平和低密度脂蛋白胆固醇水平逐渐升高。在饮食模式方面观察到微小差异。本研究表明，应根据西马哈拉施特拉邦人群的这些参考值对患者进行临床评估。
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