Effect of opioid peptides on the content of LPO products and antioxidant enzyme activity in the liver of rats after restraint stress.

作者信息

Solin A V, Lyashev Yu D

机构信息

Department of Pathophysiology, Kursk State Medical University, Ministry of Health and Social Development of the Russian Federation, Russia.

出版信息

Bull Exp Biol Med. 2012 Oct;153(6):827-9. doi: 10.1007/s10517-012-1836-z.

DOI:10.1007/s10517-012-1836-z

PMID:23113295

Abstract

Administration of opioid peptides dynorphin A (1-13) and DSLET was followed by a decrease in the stress-induced activation of LPO and increase in SOD activity in the liver tissue of rats. DAGO produced a similar, but less pronounced effect. The observed changes can be related to a specific distribution of opioid receptors in the liver tissue and stress-limiting influence of these peptides in the whole body.

摘要