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成人胆脂瘤的外科治疗:采用非分期全重建手术的长期随访

Surgical treatment of adult cholesteatoma: long-term follow-up using total reconstruction procedure without staging.

作者信息

Edfeldt Lennart, Strömbäck Karin, Kinnefors Anders, Rask-Andersen Helge

机构信息

Department of Otolaryngology, University Hospital Uppsala, Sweden.

出版信息

Acta Otolaryngol. 2013 Jan;133(1):28-34. doi: 10.3109/00016489.2012.707333. Epub 2012 Oct 31.

Abstract

CONCLUSIONS

A total of 330 cases of adult cholesteatoma were operated with canal-wall down (CWD) and total reconstruction procedure (TRP) without staging. Independent of preoperative middle ear conditions, cholesteatoma extent and localization, long-term improvement of hearing with a low incidence of residual and recurrent disease were achieved.

OBJECTIVES

To evaluate long-term surgical and hearing results using a well-defined surgical technique without staging in adult cholesteatoma.

METHODS

The same CWD surgical technique, including obliteration of the mastoid cavity, reconstruction of the canal wall, and ossiculoplasty with autologous bone, was used by three senior surgeons (1982-2004). Preoperative and postoperative pure tone average (PTA) for air conduction (AC), bone conduction (BC), and air-bone gap (ABG) were assessed and compared 1, 3, and 6 years after surgery. Various prognostic factors with potential influence on long-term hearing outcome were evaluated.

RESULTS

Recurrence of AC occurred in 10%, residual disease in 3%. Six years after surgery all patients except one had a dry ear and over 92% of all cases were water resistant. Three patients developed complete deafness. Long-lasting improvement and/or preservation of hearing, with maintenance of PTA-ABG closure in 68% of all cases within 20 dB, were obtained. Sixty-four (19%) ossicular revisions were performed.

摘要

结论

330例成人胆脂瘤患者接受了开放式乳突根治术(CWD)和全程重建手术(TRP),未进行分期手术。无论术前中耳状况、胆脂瘤范围和位置如何,均实现了听力的长期改善,残余和复发性疾病的发生率较低。

目的

使用一种明确的、不分期的手术技术评估成人胆脂瘤的长期手术和听力结果。

方法

三位资深外科医生(1982 - 2004年)采用相同的CWD手术技术,包括乳突腔填塞、耳道壁重建和自体骨听骨成形术。在术后1年、3年和6年评估并比较术前和术后气导(AC)、骨导(BC)的纯音平均听阈(PTA)以及气骨导差(ABG)。评估了各种可能对长期听力结果产生影响的预后因素。

结果

气导复发率为10%,残余疾病发生率为3%。术后6年,除1例患者外所有患者术腔干耳,超过92%的病例具备防水能力。3例患者发展为全聋。实现了听力的长期改善和/或保留,68%的病例气骨导差维持在20 dB以内。共进行了64次(19%)听骨链翻修手术。

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