Pfennig Camiron L, Slovis Corey M
Vanderbilt University Medical Center, Nashville, TN, USA.
Emerg Med Pract. 2012 Oct;14(10):1-26. Epub 2012 Sep 20.
Identifying and correcting sodium abnormalities is critical, since suboptimal management potentially leads to substantial morbidity and mortality. Manifestations of hyponatremia, which is one of the more common electrolyte abnormalities in clinical medicine, depend on multiple factors, including the chronicity of the symptoms, the absolute level of sodium, and the patient's overall health. In symptomatic hyponatremia, emergency clinicians must understand the importance of determining the proper rate of sodium correction in order to avoid encephalopathy, cerebral edema, and death. Hypernatremia is most often due to unreplaced water that is lost from the gastrointestinal tract, skin, or the urine. Acute symptomatic hypernatremia should be corrected rapidly, while chronic hypernatremia is generally corrected more slowly due to the risks of brain edema during treatment. Special circumstances do exist in sodium management, and every patient's presentation should be evaluated in clinical context.
识别并纠正钠异常至关重要,因为管理不当可能会导致严重的发病率和死亡率。低钠血症是临床医学中较常见的电解质异常之一,其表现取决于多种因素,包括症状的持续时间、钠的绝对水平以及患者的整体健康状况。在有症状的低钠血症中,急诊医生必须了解确定适当的钠纠正速率的重要性,以避免脑病、脑水肿和死亡。高钠血症最常见的原因是胃肠道、皮肤或尿液中流失的水分未得到补充。急性有症状的高钠血症应迅速纠正,而慢性高钠血症由于治疗期间存在脑水肿风险,通常纠正得更慢。在钠管理方面确实存在特殊情况,每个患者的表现都应结合临床情况进行评估。