Manuel Jennifer K, Lum Paula J, Hengl Nicholas S, Sorensen James L
Department of Psychiatry, University of California, San Francisco, CA, USA.
AIDS Care. 2013;25(7):820-7. doi: 10.1080/09540121.2012.733331. Epub 2012 Nov 2.
Smoking among people living with HIV, particularly women living with HIV, is associated with higher morbidity and mortality rates when compared to nonsmoking individuals with HIV. Despite patients' higher risk of adverse health outcomes, in particular preventable smoking-related diseases for smokers living with HIV, few smoking cessation interventions have been examined with this population. The aim of the current study was to test the potential efficacy of a brief motivational intervention for smoking cessation with HIV-infected women smokers. Participants (N=30) were randomly assigned to receive a single session of motivational interviewing (MI) or prescribed advice (PA). The primary outcome was seven-day point prevalence abstinence at the one-month follow-up interview. Secondary outcome measures included mean cigarettes smoked per day, desire to quit smoking, perceived difficulty in quitting smoking, and expectation of success. We detected no significant differences between intervention and control groups in self-reported seven-day point prevalence abstinence at the one-month follow-up. However, participants in the MI condition reported a significant decrease in the mean cigarettes smoked per day when compared to the PA condition. There were no significant between-group differences in participants' desire to quit, perceived difficulty, and expectation of success. The results of this pilot study indicate that MI may be an effective smoking cessation intervention for HIV-positive women smokers and should be studied further in a larger clinical trial.
与未感染艾滋病毒的非吸烟者相比,艾滋病毒感染者,尤其是感染艾滋病毒的女性吸烟与更高的发病率和死亡率相关。尽管患者出现不良健康结局的风险更高,特别是感染艾滋病毒的吸烟者中与吸烟相关的可预防疾病,但针对这一人群的戒烟干预措施却很少得到研究。本研究的目的是测试一种简短的动机干预对感染艾滋病毒的女性吸烟者戒烟的潜在效果。参与者(N = 30)被随机分配接受单次动机性访谈(MI)或规定建议(PA)。主要结局是在为期一个月的随访访谈中七天点患病率戒断。次要结局指标包括每天平均吸烟量、戒烟意愿、戒烟感知难度和成功期望。在为期一个月的随访中,我们未发现干预组和对照组在自我报告的七天点患病率戒断方面存在显著差异。然而,与接受规定建议的情况相比,接受动机性访谈的参与者报告每天平均吸烟量显著减少。参与者的戒烟意愿、感知难度和成功期望在组间没有显著差异。这项初步研究的结果表明,动机性访谈可能是针对艾滋病毒呈阳性的女性吸烟者的一种有效的戒烟干预措施,应在更大规模的临床试验中进一步研究。