Halalsheh Hadeel, Bazzeh Faiha, Alkayed Khaldoun, Salami Khadra, Madanat Faris
Department of Pediatric Hematology/Oncology, King Hussein Cancer Center, Amman, Jordan.
J Pediatr Hematol Oncol. 2013 Aug;35(6):470-2. doi: 10.1097/MPH.0b013e318271c92f.
Two children with acute lymphoblastic leukemia/lymphoma developed recurrent acute pancreatitis during treatment; the etiology was presumed to be secondary to 6-mercaptopurine (6MP). Both had no further attacks after discontinuation of 6MP. Acute pancreatitis secondary to 6MP is extremely rare in acute leukemia/lymphoma although it has been reported in patients with other conditions like inflammatory bowel disease; the reason for this difference is not clearly understood.
两名急性淋巴细胞白血病/淋巴瘤患儿在治疗期间出现复发性急性胰腺炎;病因推测为继发于6-巯基嘌呤(6MP)。停用6MP后两人均未再发作。6MP继发的急性胰腺炎在急性白血病/淋巴瘤中极为罕见,尽管在患有其他疾病如炎症性肠病的患者中已有报道;这种差异的原因尚不清楚。