Tiwari V K
Department of Burns and Plastic Surgery, VMMC and Safdarjung Hospital, New Delhi, India.
Indian J Plast Surg. 2012 May;45(2):364-73. doi: 10.4103/0970-0358.101319.
Management of burn injury has always been the domain of burn specialists. Since ancient time, local and systemic remedies have been advised for burn wound dressing and burn scar prevention. Management of burn wound inflicted by the different physical and chemical agents require different regimes which are poles apart from the regimes used for any of the other traumatic wounds. In extensive burn, because of increased capillary permeability, there is extensive loss of plasma leading to shock while whole blood loss is the cause of shock in other acute wounds. Even though the burn wounds are sterile in the beginning in comparison to most of other wounds, yet, the death in extensive burns is mainly because of wound infection and septicemia, because of the immunocompromised status of the burn patients. Eschar and blister are specific for burn wounds requiring a specific treatment protocol. Antimicrobial creams and other dressing agents used for traumatic wounds are ineffective in deep burns with eschar. The subeschar plane harbours the micro-organisms and many of these agents are not able to penetrate the eschar. Even after complete epithelisation of burn wound, remodelling phase is prolonged. It may take years for scar maturation in burns. This article emphasizes on how the pathophysiology, healing and management of a burn wound is different from that of other wounds.
烧伤的治疗一直是烧伤专家的领域。自古以来,就有人建议采用局部和全身疗法进行烧伤创面敷料和烧伤瘢痕预防。由不同物理和化学因素造成的烧伤创面的处理需要不同的治疗方案,这些方案与用于其他任何创伤性伤口的方案截然不同。在大面积烧伤中,由于毛细血管通透性增加,会有大量血浆流失导致休克,而在其他急性伤口中,全血流失是休克的原因。尽管与大多数其他伤口相比,烧伤创面在开始时是无菌的,但大面积烧伤患者死亡的主要原因是伤口感染和败血症,这是因为烧伤患者的免疫功能受损。焦痂和水疱是烧伤创面特有的,需要特定的治疗方案。用于创伤性伤口的抗菌乳膏和其他敷料剂对有焦痂的深度烧伤无效。焦痂下层面藏有微生物,而且许多此类药物无法穿透焦痂。即使烧伤创面完全上皮化后,重塑阶段也会延长。烧伤瘢痕成熟可能需要数年时间。本文着重阐述烧伤创面的病理生理学、愈合过程和治疗方法与其他伤口有何不同。