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憩室炎保守治疗后结肠癌的常规筛查。

Routine screening for colon cancer after conservative treatment of diverticulitis.

机构信息

Department of Surgery, Rijnstate Hospital Arnhem, Arnhem, The Netherlands.

出版信息

Dig Surg. 2012;29(5):408-11. doi: 10.1159/000345332. Epub 2012 Nov 21.

Abstract

BACKGROUND AND AIMS

It is generally advised to perform colonoscopy after conservatively treated diverticulitis because colon cancer may present itself with similar symptoms, laboratory and radiological results. With this study we investigated in what percentage of patients a malignancy was found by performing routine colonoscopy or radiologic imaging after a conservatively treated episode of diverticulitis, and whether this follow-up programme could be reserved for a selected group of patients.

METHODS

In our hospital, routine colonoscopy or, as a second choice, radiologic imaging has been standard practice over the last decade. We collected all colonoscopy and radiologic imaging results that were conducted of all 516 patients who were diagnosed with diverticulitis in this period.

RESULTS

Of those 516 patients, 378 had undergone colonoscopy, 45 radiologic imaging and 93 did not undergo any additional investigation. Eight cases of malignant neoplasia were found in those patients (2.1%), and an additional number of 40 adenomatous polyps (9.5%). Six out of 8 patients with colon cancer reported rectal blood loss, significant weight loss or persisting abdominal pain after being treated for diverticulitis.

CONCLUSIONS

In patients who were conservatively treated with routine colonoscopy or radiologic imaging for apparent diverticulitis, a malignant tumour was found in the colon in 2.1% of them. If only performed in patients reporting alarm symptoms, a case of colon cancer would be missed in only 0.5% of patients conservatively treated for diverticulitis. Therefore, screening for colon cancer after conservative treatment of diverticulitis is only indicated in symptomatic patients.

摘要

背景与目的

一般建议对经保守治疗的憩室炎患者进行结肠镜检查,因为结肠癌可能会出现类似的症状、实验室和影像学结果。本研究旨在调查在多大比例的患者中,通过对经保守治疗的憩室炎发作后进行常规结肠镜检查或影像学检查,可以发现恶性肿瘤,以及这种随访方案是否可以保留给特定的患者群体。

方法

在我们医院,近十年来,常规结肠镜检查或作为第二选择的影像学检查一直是标准做法。我们收集了在此期间诊断为憩室炎的 516 例患者中所有进行的结肠镜检查和影像学检查结果。

结果

在这 516 例患者中,378 例行结肠镜检查,45 例行影像学检查,93 例未行任何进一步检查。在这些患者中发现了 8 例恶性肿瘤(2.1%)和 40 例腺瘤性息肉(9.5%)。8 例结肠癌患者中有 6 例在接受憩室炎治疗后报告直肠出血、明显体重减轻或持续腹痛。

结论

在接受常规结肠镜检查或影像学检查保守治疗的憩室炎患者中,2.1%的患者结肠中发现恶性肿瘤。如果仅在报告报警症状的患者中进行,那么在接受憩室炎保守治疗的患者中,将有 0.5%的患者会错过结肠癌的诊断。因此,在憩室炎保守治疗后筛查结肠癌仅适用于有症状的患者。

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