一名患有长期类风湿关节炎的患者因系统性红斑狼疮导致上腔静脉综合征。

Superior vena cava syndrome caused by systemic lupus erythematosus in a patient with longstanding rheumatoid arthritis.

作者信息

van den Brink H, Vroom T M, van de Laar M A, van Soesbergen R M, van der Korst J K

机构信息

Department of Rheumatology, Slotervaart Hospital, Amsterdam, The Netherlands.

出版信息

J Rheumatol. 1990 Feb;17(2):240-3.

PMID:2319523

Abstract

Superior vena cava syndrome is mostly related to a malignant process, but many different benign causes have also been described. We report a patient with longstanding classic rheumatoid arthritis (RA), who developed a superior vena cava syndrome due to mediastinal lymphadenopathy. At that time she also fulfilled the ARA criteria for systemic lupus erythematosus (SLE). Histological examination of a lymph node biopsy revealed necrosis, hematoxylin bodies and LE cells, while a great amount of amorphous proteinaceous material was seen positive with immunofluorescence for IgG, IgM and complement (C3 and Clq). A diagnosis of superior vena cava syndrome due to mediastinal lymphadenopathy in a patient with SLE which had evolved from longstanding RA was established.

摘要

上腔静脉综合征大多与恶性病变有关，但也有许多不同的良性病因被描述过。我们报告一名患有长期典型类风湿关节炎（RA）的患者，该患者因纵隔淋巴结肿大而出现上腔静脉综合征。当时她也符合美国风湿病学会（ARA）系统性红斑狼疮（SLE）的标准。淋巴结活检的组织学检查显示有坏死、苏木精小体和狼疮细胞，同时大量无定形蛋白质物质经免疫荧光检测显示IgG、IgM和补体（C3和Clq）呈阳性。诊断为一名患有SLE的患者因纵隔淋巴结肿大导致上腔静脉综合征，该SLE由长期RA演变而来。