Oktayoglu Pelin, Cevik Figen, Tahtasiz Mehmet, Em Serda, Bozkurt Mehtap, Kapukaya Ahmet, Nas Kemal
Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Dicle University, 21280 Diyarbakir, Turkey.
Case Rep Rheumatol. 2012;2012:539310. doi: 10.1155/2012/539310. Epub 2012 Nov 8.
We describe a 31-years-old female patient with severe pain in both knees who had been diagnosed as Behcet's disease (BD) for 12 years. She had had a history of complications due to BD including superior vena cava thrombosis, pulmonary thromboembolism, uveitis, and erythema nodosum and has reported the administration of corticosteroid therapy irregularly. After radiologic evaluation, she has been diagnosed with bone infarction of both left and right knee with the existance of lupus anticoagulants (LA) positivity. Severe joint pain without the evidence of arthritis must alert the clinician to the possibility of bone necrosis of the extremity, although those may rarely occur bilateral in BD.
我们描述了一位31岁的女性患者,双膝关节剧痛,被诊断为白塞病(BD)已12年。她有白塞病相关并发症史,包括上腔静脉血栓形成、肺血栓栓塞、葡萄膜炎和结节性红斑,且曾不定期接受皮质类固醇治疗。经影像学评估,她被诊断为双侧膝关节骨梗死,同时存在狼疮抗凝物(LA)阳性。尽管在白塞病中双侧骨坏死很少见,但严重的关节疼痛且无关节炎证据时,临床医生必须警惕肢体骨坏死的可能性。