Ramírez Ocaña D, Cañada Rodríguez M J, Ruiz García J, Puentes Zarzuela C
Unidad de Gestión Clínica de Medicina Nuclear, Hospital Universitario Carlos Haya, Málaga, España.
Rev Esp Med Nucl Imagen Mol. 2013 Jul-Aug;32(4):253-6. doi: 10.1016/j.remn.2012.10.003. Epub 2012 Dec 4.
Multicentric reticulohistiocytosis is a rare systemic disease of unknown etiology. It is characterized by erosive arthritis and skin lesions. Diagnosis and treatment should be performed early to avoid sequelaes. We report the case of a 67-year-old man diagnosed with multicentric reticulohistiocytosis and left hip arthorplasty. The patient consulted for local pain in his left leg. Final diagnosis was left prosthetic dislocation. During admission, a bone scintigraphy with (99m)Tc-HDP and scintigraphy with (67)Ga-citrate was performed, showing no evidence of inflammatory activity in pelvis that contraindicating surgery. Besides it showed bilateral uptake in soft tissue of large joints compatible with persistent inflammatory activity secondary to multicentric reticulohistiocytosis. In this case scintigraphy with (67)Ga-citrate, is a useful tool to assess the recovery and extent of disease.
多中心网状组织细胞增多症是一种病因不明的罕见全身性疾病。其特征为侵蚀性关节炎和皮肤病变。应尽早进行诊断和治疗以避免后遗症。我们报告一例67岁男性诊断为多中心网状组织细胞增多症并接受左髋关节置换术的病例。该患者因左腿局部疼痛前来就诊。最终诊断为左假体脱位。住院期间,进行了(99m)Tc-HDP骨闪烁显像和(67)Ga-柠檬酸盐闪烁显像,结果显示骨盆无炎症活动迹象,不构成手术禁忌。此外,显像显示大关节软组织双侧摄取,与多中心网状组织细胞增多症继发的持续性炎症活动相符。在该病例中,(67)Ga-柠檬酸盐闪烁显像对于评估疾病的恢复情况和范围是一种有用的工具。