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一种用于区分嗅觉缺失装病者和真正嗅觉缺失患者的新测试。

A novel test to differentiate anosmic malingerers from actually anosmic patients.

机构信息

Department of Otolaryngology, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Am J Rhinol Allergy. 2012 Nov-Dec;26(6):485-8. doi: 10.2500/ajra.2012.26.3812.

Abstract

BACKGROUND

The available olfactory evaluation tests are mainly subjective methods requiring patients' collaboration. If, for any reason, the patients refuse to honestly report what they perceive, the test reliability will be questionable; this condition is potentially observable in malingering patients because of their financial or psychosocial incentives. In an olfactory discrimination test context, this study was aimed to design a test capable of distinguishing malingerer from actually anosmic or severely hyposmic patients.

METHODS

The pilot experiment of our methodology study determined five substances (coffee, lemon, rosewater, thyme, and garlic) as qualified odors of a 20-item odor discrimination test and set its normal reference value at 15. Through two simulations, 70 normosmic participants emulated actual anosmia and also malingering. The outcome results were used to measure test reliability factors.

RESULTS

During the malingering simulation, only seven participants were capable of keeping their scores at the test chance level with enough randomness in their sequences of answers while the actual anosmia simulation revealed that 39 had scores at the test chance level. Accordingly, the Tehran University Odor Discrimination Test (TUODT) was measured to have 90% sensitivity, 55.71% specificity, 67.02% positive predictive value, and 84.78%negative predictive value.

CONCLUSION

The TUODT is a relatively efficient method to identify anosmia malingerers.

摘要

背景

现有的嗅觉评估测试主要是需要患者配合的主观方法。如果由于任何原因,患者拒绝诚实地报告他们所感知到的内容,那么测试的可靠性将值得怀疑;这种情况在有经济或社会心理动机的装病患者中是潜在可观察到的。在嗅觉辨别测试的背景下,本研究旨在设计一种能够区分装病者和真正的嗅觉丧失或严重嗅觉减退患者的测试。

方法

我们方法研究的初步实验确定了五种物质(咖啡、柠檬、玫瑰水、百里香和大蒜)作为 20 项嗅觉辨别测试的合格气味,并将其正常参考值设定为 15。通过两个模拟,70 名嗅觉正常的参与者模拟了真正的嗅觉丧失和装病。测试结果用于测量测试可靠性因素。

结果

在装病模拟中,只有 7 名参与者能够在他们的答案序列中保持足够的随机性,使他们的分数保持在测试机会水平,而在实际的嗅觉丧失模拟中,有 39 名参与者的分数达到了测试机会水平。因此,德黑兰大学嗅觉辨别测试(TUODT)的灵敏度为 90%,特异性为 55.71%,阳性预测值为 67.02%,阴性预测值为 84.78%。

结论

TUODT 是一种识别嗅觉丧失装病者的相对有效方法。

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