Cameron Ian D, Gillespie Lesley D, Robertson M Clare, Murray Geoff R, Hill Keith D, Cumming Robert G, Kerse Ngaire
Rehabilitation Studies Unit, SydneyMedical School Northern, The University of Sydney, Ryde, Australia.
Cochrane Database Syst Rev. 2012 Dec 12;12:CD005465. doi: 10.1002/14651858.CD005465.pub3.
Falls in care facilities and hospitals are common events that cause considerable morbidity and mortality for older people. This is an update of a review first published in 2010.
To assess the effectiveness of interventions designed to reduce falls by older people in care facilities and hospitals.
We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (March 2012); The Cochrane Library 2012, Issue 3; MEDLINE, EMBASE, and CINAHL (all to March 2012); ongoing trial registers (to August 2012), and reference lists of articles.
Randomised controlled trials of interventions to reduce falls in older people in residential or nursing care facilities or hospitals.
Two review authors independently assessed risk of bias and extracted data. We used a rate ratio (RaR) and 95% confidence interval (CI) to compare the rate of falls (e.g. falls per person year) between intervention and control groups. For risk of falling we used a risk ratio (RR) and 95% CI based on the number of people falling (fallers) in each group. We pooled results where appropriate.
We included 60 trials (60,345 participants), 43 trials (30,373 participants) in care facilities, and 17 (29,972 participants) in hospitals.Results from 13 trials testing exercise interventions in care facilities were inconsistent. Overall, there was no difference between intervention and control groups in rate of falls (RaR 1.03, 95% CI 0.81 to 1.31; 8 trials, 1844 participants) or risk of falling (RR 1.07, 95% CI 0.94 to 1.23; 8 trials, 1887 participants). Post hoc subgroup analysis by level of care suggested that exercise might reduce falls in people in intermediate level facilities, and increase falls in facilities providing high levels of nursing care.In care facilities, vitamin D supplementation reduced the rate of falls (RaR 0.63, 95% CI 0.46 to 0.86; 5 trials, 4603 participants), but not risk of falling (RR 0.99, 95% CI 0.90 to 1.08; 6 trials, 5186 participants).For multifactorial interventions in care facilities, the rate of falls (RaR 0.78, 95% CI 0.59 to 1.04; 7 trials, 2876 participants) and risk of falling (RR 0.89, 95% CI 0.77 to 1.02; 7 trials, 2632 participants) suggested possible benefits, but this evidence was not conclusive.In subacute wards in hospital, additional physiotherapy (supervised exercises) did not significantly reduce rate of falls (RaR 0.54, 95% CI 0.16 to 1.81; 1 trial, 54 participants) but achieved a significant reduction in risk of falling (RR 0.36, 95% CI 0.14 to 0.93; 2 trials, 83 participants).In one trial in a subacute ward (54 participants), carpet flooring significantly increased the rate of falls compared with vinyl flooring (RaR 14.73, 95% CI 1.88 to 115.35) and potentially increased the risk of falling (RR 8.33, 95% CI 0.95 to 73.37).One trial (1822 participants) testing an educational session by a trained research nurse targeting individual fall risk factors in patients at high risk of falling in acute medical wards achieved a significant reduction in risk of falling (RR 0.29, 95% CI 0.11 to 0.74).Overall, multifactorial interventions in hospitals reduced the rate of falls (RaR 0.69, 95% CI 0.49 to 0.96; 4 trials, 6478 participants) and risk of falling (RR 0.71, 95% CI 0.46 to 1.09; 3 trials, 4824 participants), although the evidence for risk of falling was inconclusive. Of these, one trial in a subacute setting reported the effect was not apparent until after 45 days in hospital. Multidisciplinary care in a geriatric ward after hip fracture surgery compared with usual care in an orthopaedic ward significantly reduced rate of falls (RaR 0.38, 95% CI 0.19 to 0.74; 1 trial, 199 participants) and risk of falling (RR 0.41, 95% CI 0.20 to 0.83). More trials are needed to confirm the effectiveness of multifactorial interventions in acute and subacute hospital settings.
AUTHORS' CONCLUSIONS: In care facilities, vitamin D supplementation is effective in reducing the rate of falls. Exercise in subacute hospital settings appears effective but its effectiveness in care facilities remains uncertain due to conflicting results, possibly associated with differences in interventions and levels of dependency. There is evidence that multifactorial interventions reduce falls in hospitals but the evidence for risk of falling was inconclusive. Evidence for multifactorial interventions in care facilities suggests possible benefits, but this was inconclusive.
护理机构和医院中的跌倒事件很常见,会给老年人带来相当高的发病率和死亡率。这是对2010年首次发表的一篇综述的更新。
评估旨在减少护理机构和医院中老年人跌倒的干预措施的有效性。
我们检索了Cochrane骨、关节和肌肉创伤组专业注册库(2012年3月);《Cochrane图书馆》2012年第3期;MEDLINE、EMBASE和CINAHL(均截至2012年3月);正在进行的试验注册库(截至2012年8月)以及文章的参考文献列表。
关于减少居住或护理机构或医院中老年人跌倒的干预措施的随机对照试验。
两位综述作者独立评估偏倚风险并提取数据。我们使用率比(RaR)和95%置信区间(CI)来比较干预组和对照组之间的跌倒率(例如每人每年的跌倒次数)。对于跌倒风险,我们根据每组中跌倒的人数(跌倒者)使用风险比(RR)和95%CI。我们在适当的情况下合并结果。
我们纳入了60项试验(60345名参与者),其中43项试验(30373名参与者)在护理机构中进行,17项试验(29972名参与者)在医院中进行。在护理机构中测试运动干预措施的13项试验结果不一致。总体而言,干预组和对照组在跌倒率(RaR 1.03,95%CI 0.81至1.31;8项试验,1844名参与者)或跌倒风险(RR 1.07,95%CI 0.94至1.23;8项试验,1887名参与者)方面没有差异。根据护理水平进行的事后亚组分析表明,运动可能会减少中级护理机构中人员的跌倒,而在提供高水平护理的机构中会增加跌倒。在护理机构中,补充维生素D可降低跌倒率(RaR 0.63,95%CI 0.46至0.86;5项试验,4603名参与者),但不会降低跌倒风险(RR 0.99,95%CI 0.90至1.08;6项试验,5186名参与者)。对于护理机构中的多因素干预措施,跌倒率(RaR 0.78,95%CI 0.59至1.04;7项试验,2876名参与者)和跌倒风险(RR 0.89,95%CI 0.77至1.02;7项试验,2632名参与者)表明可能有好处,但这一证据并不确凿。在医院的亚急性病房中,额外的物理治疗(有监督的运动)并没有显著降低跌倒率(RaR 0.54,95%CI 0.16至1.81;1项试验,54名参与者),但显著降低了跌倒风险(RR 0.36,95%CI 0.14至0.93;2项试验,83名参与者)。在一项亚急性病房的试验(54名参与者)中,与乙烯基地板相比,地毯地板显著增加了跌倒率(RaR 14.73,95%CI 1.88至115.35),并可能增加了跌倒风险(RR 8.33,95%CI 0.95至73.37)。一项针对急性内科病房中跌倒高风险患者的个体跌倒风险因素进行培训的研究护士进行的教育课程试验(1822名参与者)显著降低了跌倒风险(RR 0.29,95%CI 0.11至0.74)。总体而言,医院中的多因素干预措施降低了跌倒率(RaR 0.69,95%CI 0.49至0.96;4项试验,6478名参与者)和跌倒风险(RR 0.71,95%CI 0.46至1.09;3项试验,4824名参与者),尽管关于跌倒风险的证据并不确凿。其中,一项亚急性环境中的试验报告称,直到住院45天后效果才明显。髋部骨折手术后老年病房的多学科护理与骨科病房的常规护理相比,显著降低了跌倒率(RaR 0.38,95%CI 0.19至0.74;1项试验,199名参与者)和跌倒风险(RR 0.41,95%CI 0.20至0.83)。需要更多试验来证实多因素干预措施在急性和亚急性医院环境中的有效性。
在护理机构中,补充维生素D可有效降低跌倒率。亚急性医院环境中的运动似乎有效,但由于结果相互矛盾,其在护理机构中的有效性仍不确定,这可能与干预措施和依赖程度的差异有关。有证据表明多因素干预措施可减少医院中的跌倒,但关于跌倒风险的证据并不确凿。护理机构中多因素干预措施的证据表明可能有好处,但这并不确凿。