Clinical Research Department, Centre for Addiction and Mental Health, Canada.
J Affect Disord. 2013 May;147(1-3):247-54. doi: 10.1016/j.jad.2012.11.012. Epub 2012 Dec 20.
The association between personality and psychopathology can provide an insight into the structure of mental disorders and the shared etiology and pathophysiology underlying diagnoses with overlapping symptomatology. The majority of personality-psychopathology research pertinent to the mood disorders has focused upon traits at the higher-order levels of the personality hierarchy, rather than those at intermediate or lower levels. The purpose of the current investigation was to investigate whether unipolar and bipolar mood disorders, and the severity of depressive and manic symptoms, show differential associations with traits at multiple levels of the personality hierarchy.
Participants (N=275; 63% women; mean age 42.95 years) with depressive disorders (n=139) and bipolar disorders (n=136), as assessed by the Structured Clinical Interview for DSM-IV, Axis I Disorders, Patient Version (SCID-I/P; First et al., 1995), completed the Hamilton Depression Rating Scale, Young Mania Scale, Revised NEO Personality Inventory and Big Five Aspect Scales.
Results support the hypothesis that lower levels of the personality hierarchy provide additional differentiation of affective pathology. As compared to the widespread association of depressive symptoms with traits across the personality hierarchy, manic symptoms demonstrated more specific associations with traits at lower levels of the personality hierarchy.
Patients with severe mania were excluded, thus the full range of mania is not represented in the current sample.
These results support the use of lower-order personality traits to discriminate between unipolar versus bipolar mood disorder, and are consistent with changes proposed to the psychiatric nosology to increase diagnostic precision.
人格与精神病理学之间的关联可以深入了解精神障碍的结构,以及具有重叠症状的诊断所共有的病因和病理生理学。与心境障碍相关的大多数人格-精神病理学研究都集中在人格层次结构的高阶特质上,而不是中阶或低阶特质上。本研究旨在调查单相和双相心境障碍以及抑郁和躁狂症状的严重程度是否与人格层次结构的多个层次的特质存在差异关联。
参与者(N=275;女性占 63%;平均年龄 42.95 岁)通过 DSM-IV 轴 I 障碍的结构临床访谈,患者版(SCID-I/P;First 等人,1995 年)评估为患有抑郁障碍(n=139)和双相障碍(n=136),完成了汉密尔顿抑郁评定量表、杨氏躁狂量表、修订版 NEO 人格量表和大五人格量表。
结果支持这样一种假设,即人格层次结构的较低层次可以提供对情感病理学的额外区分。与抑郁症状与人格层次结构中跨特质的广泛关联相比,躁狂症状与人格层次结构中较低层次的特质具有更特定的关联。
排除了严重躁狂的患者,因此当前样本中未包含全面的躁狂症。
这些结果支持使用较低阶人格特质来区分单相和双相心境障碍,与精神病学分类学中提出的增加诊断精度的变化一致。