骨髓增生异常综合征的自发缓解。一例病例报告。

Spontaneous remission in myelodysplastic syndrome. A case report.

作者信息

Broun E R, Heerema N A, Tricot G

机构信息

Department of Medicine, Indiana University School of Medicine, Indianapolis 46202-5250.

出版信息

Cancer Genet Cytogenet. 1990 May;46(1):125-8. doi: 10.1016/0165-4608(90)90018-6.

DOI:10.1016/0165-4608(90)90018-6

PMID:2331675

Abstract

A patient with refractory anemia with excess blasts (RAEB) and pancytopenia is reported. He was red blood cell (RBC)-transfusion dependent. Karyotype analysis showed a complex cytogenetic abnormality consisting of loss of chromosome 7 and trisomy 8. Without cytotoxic treatment, his complete blood count (CBC) subsequently became normal. He is no longer transfusion dependent and repeat cytogenetic analyses are normal.

摘要

报告了一名难治性贫血伴原始细胞增多（RAEB）和全血细胞减少的患者。他依赖红细胞（RBC）输血。核型分析显示存在复杂的细胞遗传学异常，包括7号染色体缺失和8号染色体三体。未经细胞毒性治疗，他的全血细胞计数（CBC）随后恢复正常。他不再依赖输血，重复的细胞遗传学分析也正常。